2-[2-(1H-indol-3-yl)ethylamino]-1-phenylethanol

Base Information

Chemical Name:2-[2-(1H-indol-3-yl)ethylamino]-1-phenylethanol
CAS No.:60699-85-6
Molecular Formula:C18H20N2O
Molecular Weight:280.37
Hs Code.:
DSSTox Substance ID:DTXSID801333224
Nikkaji Number:J1.578.332J
ChEMBL ID:CHEMBL1903163

Synonyms:2-[2-(1H-indol-3-yl)ethylamino]-1-phenylethanol;MLS001233629;SCHEMBL9057961;CHEMBL1903163;DTXSID801333224;HMS2902N21;AKOS034159255;SMR000596333;1-Phenyl-2-[[2-(1H-indole-3-yl)ethyl]amino]ethanol;Z31380487;60699-85-6

Suppliers and Price of 2-[2-(1H-indol-3-yl)ethylamino]-1-phenylethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-[2-(1H-indol-3-yl)ethylamino]-1-phenylethanol

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:280.157563266
Heavy Atom Count:21
Complexity:304

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(CNCCC2=CNC3=CC=CC=C32)O

Technology Process of 2-[2-(1H-indol-3-yl)ethylamino]-1-phenylethanol

There total 3 articles about 2-[2-(1H-indol-3-yl)ethylamino]-1-phenylethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 663924-10-5
N-(2-hydroxy-2-phenylethyl)-2-(1H-indol-3-yl)acetamide

: 60699-85-6
2-(2-indol-3-yl-ethylamino)-1-phenyl-ethanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; for 18h; Heating;
DOI:10.1002/ardp.200300777

Reference yield:

: 7568-93-6,1936-63-6
2-Amino-1-phenylethanol

: 60699-85-6
2-(2-indol-3-yl-ethylamino)-1-phenyl-ethanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: N,N'-carbonyldiimidazole / tetrahydrofuran / 3 h

1.2: 86 percent / tetrahydrofuran / 20 °C

2.1: 58 percent / LiAlH₄ / tetrahydrofuran; diethyl ether / 18 h / Heating

With lithium aluminium tetrahydride; 1,1'-carbonyldiimidazole; In tetrahydrofuran; diethyl ether;
DOI:10.1002/ardp.200300777