2-Oxoacetamide

Base Information

• Chemical Name: 2-Oxoacetamide
• CAS No.: 60939-21-1
• Molecular Formula: C2H3NO2
• Molecular Weight: 73.0513
• DSSTox Substance ID: DTXSID00470901
• Metabolomics Workbench ID: 60818
• Nikkaji Number: J1.127.245B
• Wikidata: Q27126919
• Mol file: 60939-21-1.mol

Synonyms:beta-oxyethylamide-n-(cyclohexylureido)-benzenesulfonyloxamic acid;glyoxamide

Chemical Property of 2-Oxoacetamide

Chemical Property:

• PSA: 60.16000
• LogP: -0.62910
• XLogP3: -1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 73.016378338
• Heavy Atom Count: 5
• Complexity: 58.7

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(=O)C(=O)N
• Uses: 2-Oxoacetamide is a reagent in bioconjugation reactions which are crucial in biotherapeutics discoveries.

Technology Process of 2-Oxoacetamide

There total 7 articles about 2-Oxoacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-propenamide (79-06-1,12624-24-7,25038-45-3,27754-57-0,33338-03-3,39387-77-4,68247-81-4,9082-06-8,79079-15-5) → formaldehyd (50-00-0,30525-89-4,61233-19-0) + α-ketoacetamide (60939-21-1)

Guidance literature:

With potassium bromate; hydrogenchloride; Hg(CH₃COO)2; at 29.85 ℃; Further Variations:; Temperatures; Kinetics;

Reference yield:

Cl6Ir(2-) + water (7732-18-5) + 2-propenamide (79-06-1,12624-24-7,25038-45-3,27754-57-0,33338-03-3,39387-77-4,68247-81-4,9082-06-8,79079-15-5) → formaldehyd (50-00-0,30525-89-4,61233-19-0) + α-ketoacetamide (60939-21-1) + Cl6Ir(3-)

Guidance literature:

In 1,4-dioxane; at 24.84 ℃; Solvent; Temperature; Time; Activation energy; Kinetics; Mechanism;

DOI:10.1002/kin.20824

Reference yield:

4-Amino-2,6-dinitrotoluene (19406-51-0,153919-64-3) → α-ketoacetamide (60939-21-1) + oxamic acid (471-47-6) + 2-oxo-propionic acid (127-17-3) + Glyoxilic acid (298-12-4)

Guidance literature:

With ozone; In water; pH=5.0; Product distribution;

DOI:10.1021/es990190h

upstream raw materials:

4-Amino-2,6-dinitrotoluene

water

2-Hexeneamide

2-propenamide

Downstream raw materials:

phenylhydrazono-acetic acid amide

C₁₄H₁₄ClN₃O₃S