(1-BENZYL-1H-INDOL-3-YL)-METHANOL

Base Information

Chemical Name:(1-BENZYL-1H-INDOL-3-YL)-METHANOL
CAS No.:60941-76-6
Molecular Formula:C16H15NO
Molecular Weight:237.301
Hs Code.:2933990090
Mol file:60941-76-6.mol

Synonyms:RARECHEM AL BD 0270;1-benzyl-3-hydroxymethyl-1H-indole;1-benzyl-3-hydroxymethylindole;1H-INDOLE-3-METHANOL,1-(PHENYLMETHYL);(1-benzyl-1H-3-indolyl)methanol;N-benzylindole-3-methanol;(1-BENZYL-1H-INDOL-3-YL)-METHANOL;1-(phenylmethyl)-1H-indole-3-methanol;N-benzyl-3-hydroxymethyl-1H-indole;

Suppliers and Price of (1-BENZYL-1H-INDOL-3-YL)-METHANOL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(Phenylmethyl)-1H-indole-3-methanol
250mg
$ 195.00

CHESS?
MC002839:(1-Benzyl-1H-indol-3-yl)-methanol 95
1 g
$ 336.00

American Custom Chemicals Corporation
(1-BENZYL-1H-INDOL-3-YL)-METHANOL 95.00%
5MG
$ 497.96

Total 4 raw suppliers

Chemical Property of (1-BENZYL-1H-INDOL-3-YL)-METHANOL

Chemical Property:

Boiling Point:456.0±33.0 °C(Predicted)
PKA:14.70±0.10(Predicted)
PSA：25.16000
Density:1.11±0.1 g/cm3(Predicted)
LogP:3.18190

Purity/Quality:

99% ^*data from raw suppliers

1-(Phenylmethyl)-1H-indole-3-methanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 1-(Phenylmethyl)-1H-indole-3-methanol is used as a reactant in dearomative indole (3 + 2) cycloaddition reactions. It is used to synthesize inhibitors of P450 aromatase.

Technology Process of (1-BENZYL-1H-INDOL-3-YL)-METHANOL

There total 8 articles about (1-BENZYL-1H-INDOL-3-YL)-METHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 10511-51-0
1-Benzylindole-3-carboxaldehyde

: 60941-76-6
1-(phenylmethyl)-1H-indole-3-methanol

Guidance literature:: With sodium tetrahydroborate; In methanol; Ambient temperature;
DOI:10.1002/ardp.19973300506

Reference yield: 39.0%

: 109-97-7,30604-81-0
pyrrole

: 10511-51-0
1-Benzylindole-3-carboxaldehyde

: 3-((1H-pyrrol-2-yl)methyl)-1-benzyl-1H-indole

: 60941-76-6
1-(phenylmethyl)-1H-indole-3-methanol

Guidance literature:: With sodium tetrahydroborate; acetic acid; In tetrahydrofuran; Reflux;
DOI:10.1016/j.tet.2021.132338

Reference yield:

: 100-44-7
benzyl chloride

: 60941-76-6
1-(phenylmethyl)-1H-indole-3-methanol

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / K₂CO₃ / acetone / Heating

2: 99 percent / NaBH₄ / methanol / Ambient temperature

With sodium tetrahydroborate; potassium carbonate; In methanol; acetone;
DOI:10.1002/ardp.19973300506