9-Hydroxyundecanoic acid methyl ester

Base Information

• Chemical Name: 9-Hydroxyundecanoic acid methyl ester
• CAS No.: 60956-81-2
• Molecular Formula: C12H24O3
• Molecular Weight: 216.31700
• Mol file: 60956-81-2.mol

Synonyms:Methyl-9-hydroxy-undecanoat;9-Hydroxy-undecanoic acid methyl ester;

Chemical Property of 9-Hydroxyundecanoic acid methyl ester

Chemical Property:

• PSA: 46.53000
• LogP: 2.66100

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9-Hydroxyundecanoic acid methyl ester

There total 3 articles about 9-Hydroxyundecanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

methyl ester of azelaic acid aldehyde (1931-63-1) + ethylmagnesium bromide (925-90-6) → methyl 9-hydroxyundecanoate (60956-81-2)

Guidance literature:

In tetrahydrofuran; at -78 ℃; for 1h; Inert atmosphere;

DOI:10.1038/s41429-019-0180-1

Reference yield:

Methyl oleate (112-62-9) → methyl 9-hydroxyundecanoate (60956-81-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 4-methylmorpholine N-oxide; ozone; oxygen / dichloromethane / 2.42 h / -78 - 20 °C

2: tetrahydrofuran / 1 h / -78 °C / Inert atmosphere

With oxygen; ozone; 4-methylmorpholine N-oxide; In tetrahydrofuran; dichloromethane;

DOI:10.1038/s41429-019-0180-1

Reference yield:

→ methyl 9-hydroxyundecanoate (60956-81-2)

Guidance literature:

Methyl-9-undecinoat, Hg(OAc)2, NaBH4;

DOI:10.1016/0009-3084(76)90025-6

upstream raw materials:

Methyl oleate

methyl ester of azelaic acid aldehyde

ethylmagnesium bromide

Refernces