2,3-Dihydro-2-oxo-1H-pyrido[2,3-b][1,4]oxazine-7-carboxylic Acid

Base Information

Chemical Name:2,3-Dihydro-2-oxo-1H-pyrido[2,3-b][1,4]oxazine-7-carboxylic Acid
CAS No.:615568-49-5
Molecular Formula:C8H6N2O4
Molecular Weight:194.14400
Hs Code.:
Mol file:615568-49-5.mol

Synonyms:2-Oxo-2,3-dihydro-1H-benzoimidazole-5-sulfonyl chloride;5-(chlorosulfonyl)-3-hydrobenzimidazol-2-one;2,3-Dihydro-2-oxo-1H-benzimidazole-5-sulfonyl chloride;2-oxo-2,3-dihydro-1H-benzimidazole-5-sulfonyl chloride;

Suppliers and Price of 2,3-Dihydro-2-oxo-1H-pyrido[2,3-b][1,4]oxazine-7-carboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,3-Dihydro-2-oxo-1H-pyrido[2,3-b][1,4]oxazine-7-carboxylicAcid
250mg
$ 165.00

AK Scientific
2-Oxo-2,3-Dihydro-1H-pyrido[2,3-b][1,4]oxazine-7-carboxylicacid
100mg
$ 692.00

Total 6 raw suppliers

Chemical Property of 2,3-Dihydro-2-oxo-1H-pyrido[2,3-b][1,4]oxazine-7-carboxylic Acid

Chemical Property:

Boiling Point:522.3±50.0 °C(Predicted)
PKA:3.37±0.20(Predicted)
PSA：92.01000
Density:1.545±0.06 g/cm3(Predicted)
LogP:0.19580

Purity/Quality:

97% ^*data from raw suppliers

2,3-Dihydro-2-oxo-1H-pyrido[2,3-b][1,4]oxazine-7-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2,3-Dihydro-2-oxo-1H-pyrido[2,3-b][1,4]oxazine-7-carboxylic Acid, is a pyridyl analogue of 3-Oxo-3,4-dihydro-2H-1,4-(benzothiazine or benzoxazine)-6-carbaldehydes, used for the studies on antibacterial medicinal chemistry.

Technology Process of 2,3-Dihydro-2-oxo-1H-pyrido[2,3-b][1,4]oxazine-7-carboxylic Acid

There total 2 articles about 2,3-Dihydro-2-oxo-1H-pyrido[2,3-b][1,4]oxazine-7-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 615568-47-3
methyl 2-oxo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine-7-formate

: 615568-49-5
2-oxo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine-7-carboxylic acid

Guidance literature:: With sodium hydroxide; water; In tetrahydrofuran; methanol; at 20 ℃; for 12h;

Reference yield:

: 615568-49-5
2-oxo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine-7-carboxylic acid

Guidance literature:

Reference yield: 74.0%

: 615568-49-5
2-oxo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine-7-carboxylic acid

: 4-((2-chloro-4-fluorophenoxy)methyl)piperidine hydrochloride

: 7-((4-((2-chloro-4-fluorophenoxy)methyl)piperidin-1-yl)carbonyl)-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 3h;
DOI:10.1021/acs.jmedchem.1c00432