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Biotinamidocaproyl hydrazide

Base Information Edit
  • Chemical Name:Biotinamidocaproyl hydrazide
  • CAS No.:109276-34-8
  • Molecular Formula:C16H29 N5 O3 S
  • Molecular Weight:371.4982
  • Hs Code.:29349990
  • European Community (EC) Number:600-909-8
  • DSSTox Substance ID:DTXSID80911069
  • Nikkaji Number:J645.131D
  • Wikidata:Q72443568
  • ChEMBL ID:CHEMBL4439291
  • Mol file:109276-34-8.mol
Biotinamidocaproyl hydrazide

Synonyms:6-BACH;biotin-6-aminocaproyl hydrazide

Suppliers and Price of Biotinamidocaproyl hydrazide
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TCI Chemical
  • N''-Biotinyl-6-aminohexanoylhydrazide >97.0%(HPLC)
  • 100mg
  • $ 194.00
  • TCI Chemical
  • N''-Biotinyl-6-aminohexanoylhydrazide >97.0%(HPLC)
  • 25mg
  • $ 63.00
  • Soltec Ventures
  • Biotinamidocaproylhydrazide
  • 50mgm
  • $ 76.50
  • Soltec Ventures
  • Biotinamidocaproylhydrazide
  • 100mgm
  • $ 144.50
  • Sigma-Aldrich
  • (+)-Biotinamidohexanoic acid hydrazide ≥90% (TLC), powder
  • 250mg
  • $ 715.00
  • Sigma-Aldrich
  • (+)-Biotinamidohexanoic acid hydrazide ≥90% (TLC), powder
  • 25mg
  • $ 85.80
  • Sigma-Aldrich
  • (+)-Biotinamidohexanoic acid hydrazide ≥90% (TLC), powder
  • 100mg
  • $ 299.00
  • purepeg
  • Hydrazide-LC-(+)-Biotin min.95%
  • 1 g
  • $ 400.00
  • Crysdot
  • N-(6-Hydrazinyl-6-oxohexyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide 97%
  • 100mg
  • $ 446.00
  • Crysdot
  • N-(6-Hydrazinyl-6-oxohexyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide 97%
  • 25mg
  • $ 179.00
Total 18 raw suppliers
Chemical Property of Biotinamidocaproyl hydrazide Edit
Chemical Property:
  • Appearance/Colour:powder 
  • Vapor Pressure:4.43E-24mmHg at 25°C 
  • Melting Point:195-196oC 
  • Boiling Point:777 °C at 760 mmHg 
  • PKA:13.26±0.35(Predicted) 
  • Flash Point:423.7 °C 
  • PSA:150.65000 
  • Density:1.188 g/cm3 
  • LogP:2.51840 
  • Storage Temp.:2-8°C 
  • Solubility.:DMSO: 25 mg/mL 
  • XLogP3:-0.3
  • Hydrogen Bond Donor Count:5
  • Hydrogen Bond Acceptor Count:5
  • Rotatable Bond Count:11
  • Exact Mass:371.19911098
  • Heavy Atom Count:25
  • Complexity:477
Purity/Quality:

98%,99%, *data from raw suppliers

N''-Biotinyl-6-aminohexanoylhydrazide >97.0%(HPLC) *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
  • Safety Statements: 22-24/25 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1C2C(C(S1)CCCCC(=O)NCCCCCC(=O)NN)NC(=O)N2
  • Isomeric SMILES:C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NCCCCCC(=O)NN)NC(=O)N2
  • Description This is a hydrazide-activated biotinylation reagent used to label glycoproteins, carbohydrate-containing compounds that have oxidizable sugars or aldehydes. Hydrazine moiety reacts with an aldehyde to form semi-permanent hydrazone bonds. The extended spacer arm helps to minimize steric hindrance.
  • Uses Biotinylation reagent with aminocaproic spacer for aldehyde groups (e.g., periodate-oxidized sugars) and carboxylic acids. Typically used for coupling to glycoproteins through the carbohydrate by hydrazone bond formation.
Technology Process of Biotinamidocaproyl hydrazide

There total 4 articles about Biotinamidocaproyl hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
Multi-step reaction with 2 steps
1: thionyl chloride / 20 °C
2: hydrazine hydrate / methanol / 17 h
With thionyl chloride; hydrazine hydrate; In methanol;
DOI:10.1016/j.bmcl.2019.01.015
Guidance literature:
Multi-step reaction with 4 steps
1: 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide / N,N-dimethyl-formamide / 8 h / 20 °C
2: sodium hydrogencarbonate / water; acetone / 12 h / 20 °C
3: thionyl chloride / 20 °C
4: hydrazine hydrate / methanol / 17 h
With 1-hydroxy-pyrrolidine-2,5-dione; thionyl chloride; hydrazine hydrate; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; In methanol; water; N,N-dimethyl-formamide; acetone;
DOI:10.1016/j.bmcl.2019.01.015
Refernces Edit
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