2,3,4-Trihydroxy-6-methylcyclohexanone

Base Information

Chemical Name:2,3,4-Trihydroxy-6-methylcyclohexanone
CAS No.:106750-01-0
Molecular Formula:C7H12 O4
Molecular Weight:160.17
Hs Code.:2914400090
Mol file:106750-01-0.mol

Synonyms:Cyclohexanone,2,3,4-trihydroxy-6-methyl-, [2S-(2a,3b,4b,6a)]-; Gabosin B; Gabosine B

Suppliers and Price of 2,3,4-Trihydroxy-6-methylcyclohexanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 2,3,4-Trihydroxy-6-methylcyclohexanone

Chemical Property:

PSA：77.76000
LogP:-1.32200

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,3,4-Trihydroxy-6-methylcyclohexanone

There total 22 articles about 2,3,4-Trihydroxy-6-methylcyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 473791-46-7
(2R,3R,4aS,6R,8R,8aS)-8-(tert-Butyl-dimethyl-silanyloxy)-2,3-dimethoxy-2,3,6-trimethyl-hexahydro-benzo[1,4]dioxin-5-one

: 106750-01-0
(2S,3R,4R,6R)-2,3,4-trihydroxy-6-methylcyclohexanone

Guidance literature:: With trifluoroacetic acid; In dichloromethane; for 17h;
DOI:10.1055/s-2002-32985

Reference yield:

: 473791-44-5
(2R,3R,4aS,8R,8aS)-8-(tert-Butyl-dimethyl-silanyloxy)-2,3-dimethoxy-2,3,6-trimethyl-2,3,8,8a-tetrahydro-4aH-benzo[1,4]dioxin-5-one

: 106750-01-0
(2S,3R,4R,6R)-2,3,4-trihydroxy-6-methylcyclohexanone

Guidance literature:: Multi-step reaction with 2 steps

1.1: H₂ / 10 percent Pd/C / methanol / 6 h

1.2: DBU / benzene / 16 h / Heating

2.1: 68 percent / aq. TFA / CH₂Cl₂ / 17 h

With hydrogen; trifluoroacetic acid; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1055/s-2002-32985

Reference yield:

: 473791-32-1
tert-Butyl-((2R,3R,4aS,5R,6S,8aR)-2,3-dimethoxy-6-methoxymethoxy-2,3-dimethyl-7-methylene-octahydro-benzo[1,4]dioxin-5-yloxy)-dimethyl-silane

: 106750-01-0
(2S,3R,4R,6R)-2,3,4-trihydroxy-6-methylcyclohexanone

Guidance literature:: Multi-step reaction with 6 steps

1.1: 54 percent / SeO₂ / pyridine N-oxide / dioxane / 16 h / Heating

2.1: 60 percent / H₂ / 10 percent Pd/C / methanol / 6 h

3.1: 67 percent / Dess-Martin periodinane / CH₂Cl₂ / 4.5 h

4.1: 81 percent / aq. NaOH / tetrahydrofuran / 3 h

5.1: H₂ / 10 percent Pd/C / methanol / 6 h

5.2: DBU / benzene / 16 h / Heating

6.1: 68 percent / aq. TFA / CH₂Cl₂ / 17 h

With sodium hydroxide; selenium(IV) oxide; hydrogen; Dess-Martin periodane; trifluoroacetic acid; pyridine N-oxide; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane;
DOI:10.1055/s-2002-32985