Benzenebutanamine, a-2-propenyl-

Base Information

• Chemical Name: Benzenebutanamine, a-2-propenyl-
• CAS No.: 625848-69-3
• Molecular Formula: C₁₃H₁₉N
• Molecular Weight: 189.301
• Mol file: 625848-69-3.mol

Synonyms:

Chemical Property of Benzenebutanamine, a-2-propenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenebutanamine, a-2-propenyl-

There total 1 articles about Benzenebutanamine, a-2-propenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-phenylbutyronitrile (2046-18-6) + allylmagnesium bromide (1730-25-2) → 4-amino-7-phenyl-1-heptene (625848-69-3)

Guidance literature:

4-phenylbutyronitrile; With diisobutylaluminium hydride; In toluene; at -78 - 20 ℃; for 6h;

allylmagnesium bromide; In diethyl ether; toluene;

DOI:10.1246/bcsj.76.1251

Reference yield:

4-amino-7-phenyl-1-heptene (625848-69-3) → methyl 2-oxo-5-(3-phenylpropyl)-1-tosyl-2-pyrrolidine acetate

Guidance literature:

Multi-step reaction with 2 steps

1: 455 mg / 4-(dimethylamino)pyridine; triethylamine / CH₂Cl₂ / 3 h

2: 70 percent / O₂ / PdCl₂; CuCl / tetrahydrofuran / 65 h / 20 °C / 760 Torr

With dmap; oxygen; triethylamine; copper(l) chloride; palladium dichloride; In tetrahydrofuran; dichloromethane;

DOI:10.1246/bcsj.76.1251

Reference yield:

4-amino-7-phenyl-1-heptene (625848-69-3) → 3-methyl-5-(3-phenylpropyl)-1-tosyl-2-pyrrolidone

Guidance literature:

Multi-step reaction with 2 steps

1: 455 mg / 4-(dimethylamino)pyridine; triethylamine / CH₂Cl₂ / 3 h

2: 86 percent / O₂ / [PdCl₂(CH₃CN)2]; CuCl / tetrahydrofuran; various solvent(s) / 27 h / 20 °C / 760 Torr

With dmap; oxygen; triethylamine; dichloro bis(acetonitrile) palladium(II); copper(l) chloride; In tetrahydrofuran; dichloromethane;

DOI:10.1246/bcsj.76.1251

upstream raw materials:

4-phenylbutyronitrile

allylmagnesium bromide

Downstream raw materials:

N-[1-(3-phenylpropyl)-3-butenyl]-p-toluenesulfonamide