5-[(3,4-Dihydroxyphenyl)methyl]imidazolidine-2,4-dione

Base Information

Chemical Name:5-[(3,4-Dihydroxyphenyl)methyl]imidazolidine-2,4-dione
CAS No.:62715-12-2
Molecular Formula:C10H10N2O4
Molecular Weight:222.2
Hs Code.:
ChEMBL ID:CHEMBL1958125
DSSTox Substance ID:DTXSID20512933

Synonyms:62715-12-2;5-[(3,4-Dihydroxyphenyl)methyl]imidazolidine-2,4-dione;SCHEMBL1011770;CHEMBL1958125;DTXSID20512933;5-(3,4-dihydroxybenzyl)-hydantoin

Suppliers and Price of 5-[(3,4-Dihydroxyphenyl)methyl]imidazolidine-2,4-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 5-[(3,4-Dihydroxyphenyl)methyl]imidazolidine-2,4-dione

Chemical Property:

XLogP3:-0.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:222.06405680
Heavy Atom Count:16
Complexity:307

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1CC2C(=O)NC(=O)N2)O)O

Technology Process of 5-[(3,4-Dihydroxyphenyl)methyl]imidazolidine-2,4-dione

There total 4 articles about 5-[(3,4-Dihydroxyphenyl)methyl]imidazolidine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 63-84-3,90638-38-3
dopa

: 917-61-3
sodium isocyanate

: 62715-12-2
5-(3,4-dihydroxybenzyl)imidazolidine-2,4-dione

Guidance literature:: dopa; sodium isocyanate; In water; at 50 ℃;

With hydrogenchloride; In water; Reflux;
DOI:10.1021/jm201243p

Reference yield:

: 4816-04-0
5-(3,4-bis-benzyloxy-benzyl)-imidazolidine-2,4-dione

: 62715-12-2
5-(3,4-dihydroxybenzyl)imidazolidine-2,4-dione

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol; for 5h; under 2327.2 Torr;
DOI:10.1021/ja00069a008

Reference yield:

: 5447-02-9
3,4-dibenzyloxybenzaldehyde

: 62715-12-2
5-(3,4-dihydroxybenzyl)imidazolidine-2,4-dione

Guidance literature:: Multi-step reaction with 3 steps

1: sodium acetate, glacial acetic acid, acetic anhydride / 3.5 h / Heating

2: 3percent sodium amalgam, H₂O / dioxane / 12 h

3: H₂, 3.0 N aq. HCl / 5percent Pd/C / ethanol / 5 h / 2327.2 Torr

With hydrogenchloride; sodium amalgam; water; hydrogen; sodium acetate; acetic anhydride; acetic acid; palladium on activated charcoal; In 1,4-dioxane; ethanol;
DOI:10.1021/ja00069a008