Dibenz[b,e]oxepin-2-carboxylicacid, 6,11-dihydro-11-[[2-[4-(phenylmethyl)-1-piperidinyl]ethyl]thio]-, sodiumsalt (1:1)

Base Information

Chemical Name:Dibenz[b,e]oxepin-2-carboxylicacid, 6,11-dihydro-11-[[2-[4-(phenylmethyl)-1-piperidinyl]ethyl]thio]-, sodiumsalt (1:1)
CAS No.:124907-31-9
Molecular Formula:C₂₉H₃₀NO₃S*Na
Molecular Weight:495.618
Hs Code.:

Synonyms:Dibenz[b,e]oxepin-2-carboxylicacid, 6,11-dihydro-11-[[2-[4-(phenylmethyl)-1-piperidinyl]ethyl]thio]-, sodiumsalt (9CI); KW 4099

Suppliers and Price of Dibenz[b,e]oxepin-2-carboxylicacid, 6,11-dihydro-11-[[2-[4-(phenylmethyl)-1-piperidinyl]ethyl]thio]-, sodiumsalt (1:1)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Dibenz[b,e]oxepin-2-carboxylicacid, 6,11-dihydro-11-[[2-[4-(phenylmethyl)-1-piperidinyl]ethyl]thio]-, sodiumsalt (1:1)

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Dibenz[b,e]oxepin-2-carboxylicacid, 6,11-dihydro-11-[[2-[4-(phenylmethyl)-1-piperidinyl]ethyl]thio]-, sodiumsalt (1:1)

There total 17 articles about Dibenz[b,e]oxepin-2-carboxylicacid, 6,11-dihydro-11-[[2-[4-(phenylmethyl)-1-piperidinyl]ethyl]thio]-, sodiumsalt (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 79669-87-7
methyl 11-oxo-6,11-dihydrodibenz[b,e]oxepin-2-carboxylate

: 124907-31-9,141364-05-8,141423-67-8,141423-68-9
sodium (+)-11-<2-(4-benzyl-1-piperidinyl)ethyl>thio-6,11-dihydrodibenzoxepine-2-carboxylate

Guidance literature:: Multi-step reaction with 5 steps

1: 96 percent / NaBH₄ / tetrahydrofuran / 1 h / 10 °C

2: 11.9 g / methanesulfonic acid / CH₂Cl₂ / 5 h / Heating

3: Lipase Amano P / ethyl acetate / 8 h / 5 °C

4: sodium methoxide / methanol / 0.5 h / 5 °C

With sodium tetrahydroborate; methanesulfonic acid; lipase Amano P; sodium methylate; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate;
DOI:10.1271/bbb.57.1157

Reference yield:

: 79669-87-7
methyl 11-oxo-6,11-dihydrodibenz[b,e]oxepin-2-carboxylate

: 124907-31-9,141364-05-8,141423-67-8,141423-68-9
sodium (-)-11-<2-(4-benzyl-1-piperidinyl)ethyl>thio-6,11-dihydrodibenzoxepine-2-carboxylate

Guidance literature:: Multi-step reaction with 5 steps

1: 96 percent / NaBH₄ / tetrahydrofuran / 1 h / 10 °C

2: 11.9 g / methanesulfonic acid / CH₂Cl₂ / 5 h / Heating

3: Lipase Amano P / ethyl acetate / 8 h / 5 °C

4: sodium methoxide / methanol / 0.5 h / 5 °C

With sodium tetrahydroborate; methanesulfonic acid; lipase Amano P; sodium methylate; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate;
DOI:10.1271/bbb.57.1157

Reference yield:

: 79670-00-1
methyl 11-methoxy-6,11-dihydrodibenz[b,e]oxepin-2-carboxylate

: 124907-31-9,141364-05-8,141423-67-8,141423-68-9
sodium (+)-11-<2-(4-benzyl-1-piperidinyl)ethyl>thio-6,11-dihydrodibenzoxepine-2-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: 11.9 g / methanesulfonic acid / CH₂Cl₂ / 5 h / Heating

2: Lipase Amano P / ethyl acetate / 8 h / 5 °C

3: sodium methoxide / methanol / 0.5 h / 5 °C

With methanesulfonic acid; lipase Amano P; sodium methylate; In methanol; dichloromethane; ethyl acetate;
DOI:10.1271/bbb.57.1157