2-(2-methyl-4-chlorophenylamino)-2-imidazoline

Base Information

• Chemical Name: 2-(2-methyl-4-chlorophenylamino)-2-imidazoline
• CAS No.: 4201-26-7
• Molecular Formula: C10H12 Cl N3
• Molecular Weight: 209.678
• Hs Code.: 2933290090
• Mol file: 4201-26-7.mol

Synonyms:2-Imidazoline,2-(4-chloro-o-toluidino)- (7CI,8CI); 2-(4-Chloro-o-toluidino)-2-imidazoline; NC7; NC 7 (pharmaceutical); St 341

Chemical Property of 2-(2-methyl-4-chlorophenylamino)-2-imidazoline

Chemical Property:

• Vapor Pressure: 0.000525mmHg at 25°C
• Boiling Point: 312.5°Cat760mmHg
• Flash Point: 142.8°C
• PSA: 36.42000
• Density: 1.31g/cm³
• LogP: 1.85690

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2-methyl-4-chlorophenylamino)-2-imidazoline

There total 3 articles about 2-(2-methyl-4-chlorophenylamino)-2-imidazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

2-Chloro-4,5-dihydro-1H-imidazole sulfate (54255-12-8) + 4-chloro-2-methylbenzeneamine (95-69-2) → (4-chloro-2-methyl-phenyl)-(4,5-dihydro-1H-imidazol-2-yl)-amine (4201-26-7)

Guidance literature:

With sodium hydroxide; dichloromethane; In methanol; water;

Reference yield:

2-[N-propargyl-N-(2'-methyl-4'-chloro-phenyl)-amino]-2-imidazoline (61939-96-6) → propargyl bromide (106-96-7) + NC 7 (4201-26-7)

Guidance literature:

Reference yield:

→ (4-chloro-2-methyl-phenyl)-(4,5-dihydro-1H-imidazol-2-yl)-amine (4201-26-7)

Guidance literature:

Ar-NH-C(=NH)SCH3, H2N(CH2)2NH2;

DOI:10.1021/jm00230a014

upstream raw materials:

2-Chloro-4,5-dihydro-1H-imidazole sulfate

4-chloro-2-methylbenzeneamine

2-[N-propargyl-N-(2'-methyl-4'-chloro-phenyl)-amino]-2-imidazoline