2-Amino-6-morpholinobenzonitrile

Base Information

Chemical Name:2-Amino-6-morpholinobenzonitrile
CAS No.:63005-74-3
Molecular Formula:C11H13N3O
Molecular Weight:203.244
Hs Code.:
DSSTox Substance ID:DTXSID20507804
Wikidata:Q82364249

Synonyms:2-amino-6-morpholinobenzonitrile;63005-74-3;SCHEMBL9513713;DTXSID20507804;BCYNGPCWTZURNL-UHFFFAOYSA-N;2-Amino-6-(morpholin-4-yl)benzonitrile

Suppliers and Price of 2-Amino-6-morpholinobenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-Amino-6-morpholinobenzonitrile

Chemical Property:

PSA：62.28000
LogP:1.62328
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:203.105862047
Heavy Atom Count:15
Complexity:254

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C2=CC=CC(=C2C#N)N

Technology Process of 2-Amino-6-morpholinobenzonitrile

There total 4 articles about 2-Amino-6-morpholinobenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 63365-42-4
6-nitro-2-morpholin-4-ylbenzenecarbonitrile

: 63005-74-3
2-amino-6-(4-morpholinyl)benzonitrile

Guidance literature:: With hydrogenchloride; iron; In methanol; for 0.25h; Heating;
DOI:10.1021/jm00138a020

Reference yield:

: 35213-00-4
2,6-dinitrobenzonitrile

: 63005-74-3
2-amino-6-(4-morpholinyl)benzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / dimethylformamide; H₂O / 0.17 h / 50 °C

2: 78 percent / Fe, conc. HCl / methanol / 0.25 h / Heating

With hydrogenchloride; iron; In methanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00138a020

Reference yield:

: 606-21-3
1-chloro-2,6-dinitrobenzene

: 63005-74-3
2-amino-6-(4-morpholinyl)benzonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / dimethylformamide / 2 h / 140 - 150 °C

2: 43 percent / dimethylformamide / 1 h / 90 °C

3: 65 percent / tin, hydrochloric acid / H₂O / 1 h / 45 °C

With hydrogenchloride; tin; In water; N,N-dimethyl-formamide;
DOI:10.1021/jm00163a067