1(3H)-Isobenzofuranone,3-hydroxy-5-methyl-(9CI)

Base Information

Chemical Name:1(3H)-Isobenzofuranone,3-hydroxy-5-methyl-(9CI)
CAS No.:63113-00-8
Molecular Formula:C9H8O3
Molecular Weight:164.15800
Hs Code.:2932209090
Mol file:63113-00-8.mol

Synonyms:3-hydroxy-5-methylisobenzofuran-1(3H)-one;2-(3-tolyl)ethanamine;RARECHEM AL BW 0213;2-(3-methylphenyl)-ethylamine;2-(3-methylphenyl)ethanamine;5-methyl-phenethyl-amine;2-m-tolylethanamine;3-Hydroxy-5-methyl 3H-isobenzofuran-1-one;2-M-TOLYL-ETHYLAMINE;5-Methylphthalaldehydsaeure;3-Hydroxy-5-methylphthalid;3-MethylphenethylaMine 1GR;

Suppliers and Price of 1(3H)-Isobenzofuranone,3-hydroxy-5-methyl-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
3-hydroxy-5-methyl-1(3H)-Isobenzofuranone 97.00%
25G
$ 6000.00

AccelPharmtech
3-hydroxy-5-methyl-1(3H)-Isobenzofuranone 97.00%
5G
$ 3230.00

AccelPharmtech
3-hydroxy-5-methyl-1(3H)-Isobenzofuranone 97.00%
1G
$ 1890.00

Total 11 raw suppliers

Chemical Property of 1(3H)-Isobenzofuranone,3-hydroxy-5-methyl-(9CI)

Chemical Property:

Boiling Point:380.7±42.0 °C(Predicted)
PKA:10.97±0.20(Predicted)
PSA：46.53000
Density:1.375±0.06 g/cm3(Predicted)
LogP:1.15630

Purity/Quality:

99% ^*data from raw suppliers

3-hydroxy-5-methyl-1(3H)-Isobenzofuranone 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1(3H)-Isobenzofuranone,3-hydroxy-5-methyl-(9CI)

There total 11 articles about 1(3H)-Isobenzofuranone,3-hydroxy-5-methyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: N,N-diethyl-2-formyl-4-methyl-benzamide

: 63113-00-8
3-hydroxy-5-methylisobenzofuran-1(3H)-one

Guidance literature:: In hydrogenchloride; water;

Reference yield:

: 63113-10-0
5-(bromomethyl)-1,3-dihydroisobenzofuran-1-one

: 63113-00-8
3-hydroxy-5-methylisobenzofuran-1(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / H₂, Ca(OH)2 / 10percent Pd/C / dioxane / 48 h / 2068.6 Torr

2: 1.) NBS, benzoyl peroxide, 2.) H₂O / 1.) CCl₄, reflux, 1 h, 2.) reflux

With calcium hydroxide; N-Bromosuccinimide; Perbenzoic acid; water; hydrogen; palladium on activated charcoal; In 1,4-dioxane;
DOI:10.1007/BF00807401

Reference yield:

: 23617-71-2
2,4-dimethyl-benzoic acid methyl ester

: 63113-00-8
3-hydroxy-5-methylisobenzofuran-1(3H)-one

Guidance literature:: Multi-step reaction with 4 steps

1: NBS, benzoyl peroxide / CCl₄ / 3 h / Heating

2: 1 h / 180 °C / 10 Torr

3: 83 percent / H₂, Ca(OH)2 / 10percent Pd/C / dioxane / 48 h / 2068.6 Torr

4: 1.) NBS, benzoyl peroxide, 2.) H₂O / 1.) CCl₄, reflux, 1 h, 2.) reflux

With calcium hydroxide; N-Bromosuccinimide; Perbenzoic acid; water; hydrogen; palladium on activated charcoal; In 1,4-dioxane; tetrachloromethane;
DOI:10.1007/BF00807401