[1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 6-bromo-5-methyl-

Base Information

Chemical Name:[1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 6-bromo-5-methyl-
CAS No.:32449-41-5
Molecular Formula:C6H5 Br N4 O
Molecular Weight:229.036
Hs Code.:2933990090
European Community (EC) Number:251-052-8
DSSTox Substance ID:DTXSID0067686
Nikkaji Number:J1.012.902H,J319.387J
Mol file:32449-41-5.mol

Synonyms:32449-41-5;41081-77-0;[1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 6-bromo-5-methyl-;6-Bromo-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one;C6H5BrN4O;6-Bromo-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7(3H)-one;6-bromo-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-ol;(1,2,4)Triazolo(1,5-a)pyrimidin-7-ol, 6-bromo-5-methyl-;EINECS 251-052-8;ChemDiv1_008833;SCHEMBL457105;DTXSID0067686;HMS612B11;PBADSWFRDNMCQD-UHFFFAOYSA-N;6-bromo-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(3H)-one;STK375819;STK709249;STL333784;AKOS000676576;AKOS002663057;AKOS003194195;EU-0076826;SR-01000414507;SR-01000480475;SR-01000414507-1;SR-01000480475-1;5-bromo-4-hydroxy-6-methyl-1,3,3a,7-tetraazaindene;6-Bromo-5-methyl-1,2,4-triazolo(1,5-a)pyrimidin-7-ol;[1,2,4]Triazolo[1,5-a]pyrimidin-7(4H)-one, 6-bromo-5-methyl-;6-Bromo-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one #

Suppliers and Price of [1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 6-bromo-5-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of [1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 6-bromo-5-methyl-

Chemical Property:

Melting Point:269 °C(Solv: water (7732-18-5))
Boiling Point:271.6°Cat760mmHg
PKA:-2.20±0.53(Predicted)
Flash Point:118.1°C
PSA：63.05000
Density:2.16g/cm³
LogP:0.48850
XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:227.96467
Heavy Atom Count:12
Complexity:344

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=O)N2C(=N1)N=CN2)Br

Technology Process of [1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 6-bromo-5-methyl-

There total 2 articles about [1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 6-bromo-5-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 103109-39-3
2,3-diamino-5-bromo-6-methyl-4(3H)-pyrimidinone

: 122-51-0
orthoformic acid triethyl ester

: 32449-41-5
6-bromo-5-methyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one

Guidance literature:: In acetic acid; for 2h; Heating;

Reference yield:

: 32449-41-5
6-bromo-5-methyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one

Guidance literature:: Triazolopyrimidin I, Br2;

Reference yield:

: 32449-41-5
6-bromo-5-methyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one

: C₁₉H₂₃N₅OS

Guidance literature:: Multi-step reaction with 4 steps

1: trichlorophosphate / 105 °C

2: acetonitrile / 1 h

3: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium carbonate; tri tert-butylphosphoniumtetrafluoroborate / water; 1,2-dimethoxyethane / 12 h / 80 °C

4: [bis(acetoxy)iodo]benzene; ammonium carbamate / methanol / 1 h

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; ammonium carbamate; [bis(acetoxy)iodo]benzene; sodium carbonate; tri tert-butylphosphoniumtetrafluoroborate; trichlorophosphate; In methanol; 1,2-dimethoxyethane; water; acetonitrile;