Pyrano(2,3-g)indol-9(1H)-one, 7,8-dihydro-5-methoxy-

Base Information

Chemical Name:Pyrano(2,3-g)indol-9(1H)-one, 7,8-dihydro-5-methoxy-
CAS No.:81258-07-3
Molecular Formula:C₁₂H₁₁NO₃
Molecular Weight:217.224
Hs Code.:
DSSTox Substance ID:DTXSID30230999
Wikidata:Q83111802

Synonyms:Pyrano(2,3-g)indol-9(1H)-one, 7,8-dihydro-5-methoxy-;81258-07-3;5-methoxy-7,8-dihydro-1H-pyrano[2,3-g]indol-9-one;7,8-Dihydro-5-methoxypyrano(2,3-g)indol-9(1H)-one;5-Methoxy-9-oxo-7,8-dihydro-pyranno(2,3-g)indole [French];5-Methoxy-9-oxo-7,8-dihydro-pyranno(2,3-g)indole;Oprea1_762715;SCHEMBL10746694;DTXSID30230999;AO-079/15259047;5-methoxy-7,8-dihydropyrano[2,3-g]indol-9(1H)-one

Suppliers and Price of Pyrano(2,3-g)indol-9(1H)-one, 7,8-dihydro-5-methoxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Pyrano(2,3-g)indol-9(1H)-one, 7,8-dihydro-5-methoxy-

Chemical Property:

Vapor Pressure:1.09E-08mmHg at 25°C
Boiling Point:461.3°Cat760mmHg
Flash Point:232.8°C
Density:1.355g/cm³
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:217.07389321
Heavy Atom Count:16
Complexity:294

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C2C(=C3C(=C1)C=CN3)C(=O)CCO2

Technology Process of Pyrano(2,3-g)indol-9(1H)-one, 7,8-dihydro-5-methoxy-

There total 9 articles about Pyrano(2,3-g)indol-9(1H)-one, 7,8-dihydro-5-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 81258-05-1
acide methoxy-5 oxo-9 dihydro-7,8 pyranno<2,3-g>indolecarboxylique-2

: 81258-07-3
5-methoxy-7,8-dihydropyrano<2,3-g>indol-9

Guidance literature:: copper chromite; In quinoline;

Reference yield: 54.0%

: 81258-05-1
acide methoxy-5 oxo-9 dihydro-7,8 pyranno<2,3-g>indolecarboxylique-2

: 83868-34-2
acetyl-7 hydroxy-6 methoxy-5 indole

: 81258-07-3
5-methoxy-7,8-dihydropyrano<2,3-g>indol-9

Guidance literature:: With chromium(III) oxide; copper(II) oxide; In quinoline; for 13h;
DOI:10.1139/v82-299

Reference yield:

: 7368-78-7
4-bromoguaiacol

: 81258-07-3
5-methoxy-7,8-dihydropyrano<2,3-g>indol-9

Guidance literature:: Multi-step reaction with 9 steps

1: 1) NaOH / 1) H₂O, reflux, 15 min; 2) H₂O, reflux, 50 min

2: 1) H₃PO₄, P₂O₅ / 1) benzene, 4 h, reflux; 2) benzene 12 h, reflux

3: 82 percent / 3 percent p-toluenesulfonic acid / toluene / 7 h / Heating

4: 1) n-BuLi / 1) ether, -70 deg C, 6 h; 2) ether, 12 h, -70 deg C

5: Na / methanol / 168 h / 0 °C

6: xylene / 3 h / Heating

7: conc. HCl, H₂O / ethanol / 18 h

8: 93 percent / KOH, H₂O

9: 54 percent / CuO, Cr₂O₃ / quinoline / 13 h

With hydrogenchloride; chromium(III) oxide; potassium hydroxide; sodium hydroxide; n-butyllithium; phosphoric acid; water; sodium; phosphorus pentoxide; toluene-4-sulfonic acid; copper(II) oxide; In quinoline; methanol; ethanol; toluene; xylene;
DOI:10.1139/v82-299