9-Amino-2-methylacridine

Base Information

• Chemical Name: 9-Amino-2-methylacridine
• CAS No.: 23045-12-7
• Molecular Formula: C14H12 N2
• Molecular Weight: 208.2585
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID20177607
• Nikkaji Number: J66.893A
• Wikidata: Q83047922
• ChEMBL ID: CHEMBL357429
• Mol file: 23045-12-7.mol

Synonyms:2-methylacridin-9-amine;9-Amino-2-methylacridine;23045-12-7;CCRIS 7984;ACRIDINE, 9-AMINO-2-METHYL-;5-Amino-3-methylacridine (European);9-Acridinamine, 2-methyl-;BRN 0159614;5-22-11-00073 (Beilstein Handbook Reference);9-Acridinamine,2-methyl-;CHEMBL357429;SCHEMBL13696862;DTXSID20177607;D87078

Chemical Property of 9-Amino-2-methylacridine

Chemical Property:

• Vapor Pressure: 2.01E-07mmHg at 25°C
• Boiling Point: 424.8°Cat760mmHg
• Flash Point: 240.3°C
• PSA: 39.64000
• Density: 1.229g/cm³
• LogP: 3.20870
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 208.100048391
• Heavy Atom Count: 16
• Complexity: 253

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC2=C(C3=CC=CC=C3N=C2C=C1)N

Technology Process of 9-Amino-2-methylacridine

There total 6 articles about 9-Amino-2-methylacridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

9-chloro-2-methylacridine (16492-09-4) → 2-methyl-9-aminoacridine (23045-12-7)

Guidance literature:

With sodium tetrahydroborate; sodium azide; tetrabutylammomium bromide; Yield given. Multistep reaction; 1.) H₂O/CH₂Cl₂, room temp., 1 h; 2.) room temp., 2 h;

Reference yield:

para-bromotoluene (106-38-7) → 2-methyl-9-aminoacridine (23045-12-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 3.9 percent / Na₂CO₃, Cu / butan-1-ol / 24 h / Heating

With copper; sodium carbonate; In butan-1-ol;

DOI:10.1271/bbb.61.1121

Reference yield:

anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4) → 2-methyl-9-aminoacridine (23045-12-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 3.9 percent / Na₂CO₃, Cu / butan-1-ol / 24 h / Heating

With copper; sodium carbonate; In butan-1-ol;

DOI:10.1271/bbb.61.1121

upstream raw materials:

9-chloro-2-methylacridine

N-p-tolyl-anthranilic acid

para-bromotoluene

anthranilic acid

Downstream raw materials:

9-amino-7-methyl-1,2,3,4-tetrahydroacridine