(2S,4AR,6aR,7R,10R,10aS,10bS)-2-(furan-3-yl)-7-hydroxy-6a,10b-dimethyl-4a,5,6,6a,7,10,10a,10b-octahydro-1H-10,7-(epoxymethano)benzo[f]isochromene-4,12(2H)-dione

Base Information Edit

Chemical Name:(2S,4AR,6aR,7R,10R,10aS,10bS)-2-(furan-3-yl)-7-hydroxy-6a,10b-dimethyl-4a,5,6,6a,7,10,10a,10b-octahydro-1H-10,7-(epoxymethano)benzo[f]isochromene-4,12(2H)-dione
CAS No.:546-97-4
Molecular Formula:C20H22O6
Molecular Weight:358.391
Hs Code.:29322090
DSSTox Substance ID:DTXSID70969857
Nikkaji Number:J9.412I
Wikidata:Q27106207
Mol file:546-97-4.mol

(2S,4AR,6aR,7R,10R,10aS,10bS)-2-(furan-3-yl)-7-hydroxy-6a,10b-dimethyl-4a,5,6,6a,7,10,10a,10b-octahydro-1H-10,7-(epoxymethano)benzo[f]isochromene-4,12(2H)-dione

Synonyms:4-hydroxy-15,16-epoxycleroda-2,13(16),14-trieno-17,12-18,1-biscarbolactone;columbin

Suppliers and Price of (2S,4AR,6aR,7R,10R,10aS,10bS)-2-(furan-3-yl)-7-hydroxy-6a,10b-dimethyl-4a,5,6,6a,7,10,10a,10b-octahydro-1H-10,7-(epoxymethano)benzo[f]isochromene-4,12(2H)-dione

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Columbin
1mg
$ 50.00

TRC
Columbin
5mg
$ 155.00

Sigma-Aldrich
Columbin ≥95% (LC/MS-ELSD)
1mg
$ 233.00

DC Chemicals
Columbin >98%,StandardReferencesGrade
20 mg
$ 280.00

ChemScene
Columbin 98.86%
10mg
$ 96.00

ChemScene
Columbin 98.86%
5mg
$ 60.00

ChemScene
Columbin 98.86%
25mg
$ 192.00

ChemScene
Columbin 98.86%
50mg
$ 336.00

Cayman Chemical
Columbin ≥98%
25mg
$ 474.00

Cayman Chemical
Columbin ≥98%
10mg
$ 209.00

Total 43 raw suppliers

Chemical Property of (2S,4AR,6aR,7R,10R,10aS,10bS)-2-(furan-3-yl)-7-hydroxy-6a,10b-dimethyl-4a,5,6,6a,7,10,10a,10b-octahydro-1H-10,7-(epoxymethano)benzo[f]isochromene-4,12(2H)-dione Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:190-191oC
Refractive Index:1.4450 (estimate)
Boiling Point:565.9°Cat760mmHg
PKA:12.14±0.70(Predicted)
Flash Point:296°C
PSA：85.97000
Density:1.36g/cm³
LogP:2.53270
Storage Temp.:?20°C
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:358.14163842
Heavy Atom Count:26
Complexity:702

Purity/Quality:

98% ^*data from raw suppliers

Columbin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC3C(=O)OC(CC3(C1C4C=CC2(C(=O)O4)O)C)C5=COC=C5
Isomeric SMILES:C[C@@]12CC[C@H]3C(=O)O[C@@H](C[C@]3([C@@H]1[C@H]4C=C[C@@]2(C(=O)O4)O)C)C5=COC=C5
Uses Columbin is a furanolactone diterpene isolated from the roots of Jateorhiza and Tinospora species and is used in Asian and African folk medicine for analgesic and antipyretic properties.

Technology Process of (2S,4AR,6aR,7R,10R,10aS,10bS)-2-(furan-3-yl)-7-hydroxy-6a,10b-dimethyl-4a,5,6,6a,7,10,10a,10b-octahydro-1H-10,7-(epoxymethano)benzo[f]isochromene-4,12(2H)-dione

There total 2 articles about (2S,4AR,6aR,7R,10R,10aS,10bS)-2-(furan-3-yl)-7-hydroxy-6a,10b-dimethyl-4a,5,6,6a,7,10,10a,10b-octahydro-1H-10,7-(epoxymethano)benzo[f]isochromene-4,12(2H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: