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Technology Process of Pitavastatin Lactone

Pitavastatin Lactone

Base Information
  • Chemical Name:Pitavastatin Lactone
  • CAS No.:141750-63-2
  • Molecular Formula:C25H22FNO3
  • Molecular Weight:403.45
  • Hs Code.:
  • UNII:ULK88EV7VQ
  • Nikkaji Number:J671.624E
  • Mol file:141750-63-2.mol
Pitavastatin Lactone

Synonyms:(E,3R,5S)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoic acid;itavastatin;itavastatin calcium;nisvastatin;NK 104;NK-104;P 872441;P-872441;pitavastatin;pitavastatin calcium;pitavastatin lactone

Suppliers and Price of Pitavastatin Lactone
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Cayman Chemical
  • Pitavastatin lactone ≥98%
  • 1mg
  • $ 45.00
  • Cayman Chemical
  • Pitavastatin lactone ≥98%
  • 500μg
  • $ 25.00
  • Cayman Chemical
  • Pitavastatin lactone ≥98%
  • 5mg
  • $ 188.00
  • Biosynth Carbosynth
  • Pitavastatin lactone
  • 10 mg
  • $ 95.00
  • American Custom Chemicals Corporation
  • PITAVASTATIN LACTONE 95.00%
  • 50MG
  • $ 1758.49
  • American Custom Chemicals Corporation
  • PITAVASTATIN LACTONE 95.00%
  • 5MG
  • $ 730.54
Total 69 raw suppliers
Chemical Property of Pitavastatin Lactone
Chemical Property:
  • Appearance/Colour:White to off-white powder 
  • Vapor Pressure:1.94E-19mmHg at 25°C 
  • Melting Point:92-95 °C 
  • Refractive Index:1.727 
  • Boiling Point:616.929 °C at 760 mmHg 
  • PKA:13.25±0.40(Predicted) 
  • Flash Point:326.907 °C 
  • PSA：59.42000 
  • Density:1.373 g/cm3 
  • LogP:4.99800 
  • Storage Temp.:Hygroscopic, -20°C Freezer, Under Inert Atmosphere 
  • Solubility.:Chloroform 
  • XLogP3:4.3
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:5
  • Rotatable Bond Count:4
  • Exact Mass:403.15837173
  • Heavy Atom Count:30
  • Complexity:642
Purity/Quality:

97% *data from raw suppliers

Pitavastatin lactone ≥98% *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1CC1C2=NC3=CC=CC=C3C(=C2C=CC4CC(CC(=O)O4)O)C5=CC=C(C=C5)F
  • Isomeric SMILES:C1CC1C2=NC3=CC=CC=C3C(=C2/C=C/[C@@H]4C[C@H](CC(=O)O4)O)C5=CC=C(C=C5)F
  • Uses Lactone form of Pitavastatin; a HMG-CoA reductase inhibitor. Recent studies have shown that conversion between acid and lactone forms occurs in the body, drug-drug interaction should be considered on both acid and lactone forms.
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