Parnate

Base Information

Chemical Name:Parnate
CAS No.:3721-26-4
Deprecated CAS:95-62-5
Molecular Formula:C₉H₁₁N
Molecular Weight:133.193
Hs Code.:
European Community (EC) Number:205-841-9
UNII:3E3V44J4Z9
DSSTox Substance ID:DTXSID2023694,DTXSID201015773
Nikkaji Number:J9.122G
Wikipedia:Tranylcypromine
Wikidata:Q100429273
NCI Thesaurus Code:C61979
RXCUI:10734
Pharos Ligand ID:LM1GZFVJ9TM4
ChEMBL ID:CHEMBL1179
Mol file:3721-26-4.mol

Synonyms:Jatrosom;Parnate;Sulfate, Tranylcypromine;trans 2 Phenylcyclopropylamine;trans-2-Phenylcyclopropylamine;Transamine;Tranylcypromine;Tranylcypromine Sulfate

Suppliers and Price of Parnate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
(1R,2S)-2-Phenyl-cyclopropylamine 95%
5g
$ 1998.00

J&W Pharmlab
(1R,2S)-2-Phenyl-cyclopropylamine 95%
100mg
$ 144.00

J&W Pharmlab
(1R,2S)-2-Phenyl-cyclopropylamine 95%
50mg
$ 122.00

J&W Pharmlab
(1R,2S)-2-Phenyl-cyclopropylamine 95%
500mg
$ 275.00

J&W Pharmlab
(1R,2S)-2-Phenyl-cyclopropylamine 95%
250mg
$ 188.00

J&W Pharmlab
(1R,2S)-2-Phenyl-cyclopropylamine 95%
1g
$ 450.00

Crysdot
(1R,2S)-2-Phenylcyclopropanamine 95+%
1g
$ 330.00

Crysdot
(1R,2S)-2-Phenylcyclopropanamine 95+%
5g
$ 990.00

Chemenu
(1R,2S)-2-phenylcyclopropan-1-amine 95+%
10g
$ 644.00

Ambeed
(1R,2S)-2-Phenylcyclopropanamine 95%
1g
$ 306.00

Total 8 raw suppliers

Chemical Property of Parnate

Chemical Property:

Boiling Point:218.3°Cat760mmHg
PKA:8.24±0.10(Predicted)
Flash Point:90.8°C
PSA：26.02000
Density:1.065g/cm³
LogP:2.20150
Storage Temp.:2-8°C(protect from light)
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:133.089149355
Heavy Atom Count:10
Complexity:116

Purity/Quality:

97% ^*data from raw suppliers

(1R,2S)-2-Phenyl-cyclopropylamine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Drug Classes:Antidepressant Agents
Canonical SMILES:C1C(C1N)C2=CC=CC=C2
Isomeric SMILES:C1[C@H]([C@@H]1N)C2=CC=CC=C2
Recent ClinicalTrials:Study of TCP-ATRA for Adult Patients With AML and MDS
Recent EU Clinical Trials:Phase I/II pilot trial of ATRA (Tretinoin) and TCP (Tranylcypromine) in patients with relapsed or refractory acute myeloid leukemia (AML) when no intensive treatment is possible

Technology Process of Parnate

There total 40 articles about Parnate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: C₁₇H₂₃NO₂

: 95-62-5,155-09-9,3721-26-4,3721-28-6,13531-35-6,24873-95-8,69684-88-4,69684-89-5,54-97-7
(1R,2S)-1-amino-2-phenylcyclopropane

Guidance literature:: With trifluoroacetic acid; In 1,4-dioxane; water; for 21h;
DOI:10.1055/s-2008-1072786

Reference yield: 79.0%

: 1444-65-1
(RS)-2-phenylcyclohexanone

: 93-92-5,50373-55-2
1-phenylethyl acetate

: 95-62-5,155-09-9,3721-26-4,3721-28-6,13531-35-6,24873-95-8,69684-88-4,69684-89-5,54-97-7
(1R,2S)-1-amino-2-phenylcyclopropane

: 37982-23-3
(+)-(1S,2R)-2-Phenylcyclohexanamine

: 312611-48-6
(1R,2S)-N-(2-phenylcyclohexyl)acetamide

: 1011-11-6,17293-45-7,22147-09-7,37982-23-3,37982-28-8,37982-29-9,40960-61-0,46175-82-0,69743-67-5
cis-1-amino-2-phenylcyclohexane

Guidance literature:: (RS)-2-phenylcyclohexanone; With ammonium formate; palladium on activated charcoal; In methanol; water; at 20 ℃;

1-phenylethyl acetate; With Novozyme 435 immobilized on polyacrylamide;
DOI:10.1016/j.tetasy.2005.07.033