N-(4-methylphenyl)-2-nitrobenzenesulfonamide

Base Information

Chemical Name:N-(4-methylphenyl)-2-nitrobenzenesulfonamide
CAS No.:63228-66-0
Molecular Formula:C13H12N2O4S
Molecular Weight:292.315
Hs Code.:
Mol file:63228-66-0.mol

Synonyms:2-Nitro-benzolsulfonsaeure-p-toluidid;2-nitro-benzenesulfonic acid p-toluidide;

Suppliers and Price of N-(4-methylphenyl)-2-nitrobenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-(4-METHYLPHENYL)-2-NITROBENZENESULFONAMIDE 95.00%
5MG
$ 500.40

Total 0 raw suppliers

Chemical Property of N-(4-methylphenyl)-2-nitrobenzenesulfonamide

Chemical Property:

PSA：100.37000
LogP:4.38100

Purity/Quality:: N-(4-METHYLPHENYL)-2-NITROBENZENESULFONAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-(4-methylphenyl)-2-nitrobenzenesulfonamide

There total 1 articles about N-(4-methylphenyl)-2-nitrobenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 106-49-0,12221-03-3
p-toluidine

: 1694-92-4
2-Nitrobenzenesulfonyl chloride

: 63228-66-0
N-(4'-methylphenyl)-2-nitrobenzenesulfonamide

Guidance literature:: With sodium acetate; In methanol; water; at 60 ℃; for 1h;
DOI:10.1002/ejoc.200900113

Reference yield: 93.0%

: 63228-66-0
N-(4'-methylphenyl)-2-nitrobenzenesulfonamide

: (4S,5S)-4-{3-[(tert-butyldimethylsilyl)oxy]propyl}-5-(hydroxymethyl)-1,3-oxazolidin-2-one

: (4S,5R)-4-(3-hydroxypropyl)-5-{(4-methylphenyl)[(2-nitrophenyl)sulfonyl]amino}methyl-1,3-oxazolidin-2-one

Guidance literature:: N-(4'-methylphenyl)-2-nitrobenzenesulfonamide; (4S,5S)-4-{3-[(tert-butyldimethylsilyl)oxy]propyl}-5-(hydroxymethyl)-1,3-oxazolidin-2-one; With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 3h;

With hydrogenchloride; In tetrahydrofuran; water; at 0 - 20 ℃; for 0.5h;
DOI:10.1016/j.bmc.2021.116517

Reference yield: 90.0%

: 63228-66-0
N-(4'-methylphenyl)-2-nitrobenzenesulfonamide

: (4S,5S)-4-{2-[(tert-butyldimethylsilyl)oxy]ethyl}-5-(hydroxymethyl)-1,3-oxazolidin-2-one

: (4S,5R)-4-(2-hydroxyethyl)-5-{(4-methylphenyl)[(2-nitrophenyl)sulfonyl]amino}methyl-1,3-oxazolidin-2-one

Guidance literature:: N-(4'-methylphenyl)-2-nitrobenzenesulfonamide; (4S,5S)-4-{2-[(tert-butyldimethylsilyl)oxy]ethyl}-5-(hydroxymethyl)-1,3-oxazolidin-2-one; With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 3h;

With hydrogenchloride; In tetrahydrofuran; water; at 0 - 20 ℃; for 0.5h;
DOI:10.1016/j.bmc.2021.116517