3-(2-Naphtyl)-4-hydroxycoumarin

Base Information

Chemical Name:3-(2-Naphtyl)-4-hydroxycoumarin
CAS No.:73791-16-9
Molecular Formula:C₁₉H₁₂O₃
Molecular Weight:288.302
Hs Code.:
Mol file:73791-16-9.mol

Synonyms:4-hydroxy-3-(2-naphthalenyl)coumarin;2H-1-Benzopyran-2-one,4-hydroxy-3-(2-naphthyl);2-hydroxy-3-naphthalen-2-ylchromen-4-one;4-hydroxy-3-naphthalen-2-yl-chromen-2-one;4-Hydroxy-3-<2-naphthyl>-cumarin;

Suppliers and Price of 3-(2-Naphtyl)-4-hydroxycoumarin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-(2-Naphtyl)-4-hydroxycoumarin

Chemical Property:

Vapor Pressure:3.13E-10mmHg at 25°C
Boiling Point:485.3°Cat760mmHg
Flash Point:181.6°C
PSA：50.44000
Density:1.383g/cm³
LogP:4.31880

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-(2-Naphtyl)-4-hydroxycoumarin

There total 3 articles about 3-(2-Naphtyl)-4-hydroxycoumarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 32316-92-0
naphthalene-2-boronic acid

: 86795-49-5
3-(phenyl-λ³-iodanylidene)chromane-2,4-dione

: 73791-16-9
4-Hydroxy-3-<2-naphthyl>-cumarin

Guidance literature:: With lithium hydroxide; tri-tert-butyl phosphine; palladium diacetate; In 1,2-dimethoxyethane; water; at 25 ℃; for 14h;
DOI:10.1021/ol020159b

Reference yield:

: 1076-38-6,92395-12-5
4-hydroxy[1]benzopyran-2-one

: 73791-16-9
4-Hydroxy-3-<2-naphthyl>-cumarin

Guidance literature:: Multi-step reaction with 2 steps

1.1: Na₂CO₃ / H₂O / 0.5 h / 20 °C

1.2: Na₂CO₃ / H₂O / 2 h / 20 °C

2.1: 80 percent / LiOH*H₂O; P(t-Bu)3 / Pd(OAc)2 / 1,2-dimethoxy-ethane; H₂O / 14 h / 25 °C

With lithium hydroxide; tri-tert-butyl phosphine; sodium carbonate; palladium diacetate; In 1,2-dimethoxyethane; water; 2.1: Suzuki coupling reaction;
DOI:10.1021/ol020159b