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2-Indolizinecarboxylic acid, 3-phenyl-, ethyl ester

Base Information Edit
  • Chemical Name:2-Indolizinecarboxylic acid, 3-phenyl-, ethyl ester
  • CAS No.:63273-06-3
  • Molecular Formula:C17H15NO2
  • Molecular Weight:265.312
  • Hs Code.:
  • Mol file:63273-06-3.mol
2-Indolizinecarboxylic acid, 3-phenyl-, ethyl ester

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Chemical Property of 2-Indolizinecarboxylic acid, 3-phenyl-, ethyl ester Edit
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Technology Process of 2-Indolizinecarboxylic acid, 3-phenyl-, ethyl ester

There total 7 articles about 2-Indolizinecarboxylic acid, 3-phenyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With water; potassium acetate; bis-triphenylphosphine-palladium(II) chloride; In 1-methyl-pyrrolidin-2-one; at 100 ℃; for 7h;
DOI:10.1021/ol049866q
Guidance literature:
With bis-triphenylphosphine-palladium(II) chloride; potassium acetate; In 1,4-dioxane; at 90 - 110 ℃;
DOI:10.1016/j.bmcl.2012.09.059
Guidance literature:
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / ethanol / 120 °C
2: bis-triphenylphosphine-palladium(II) chloride; potassium acetate / 1,4-dioxane / 90 - 110 °C
With bis-triphenylphosphine-palladium(II) chloride; potassium acetate; sodium hydrogencarbonate; In 1,4-dioxane; ethanol; 2: |Heck Reaction;
DOI:10.1016/j.bmcl.2012.09.059
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