Chemical Property of 3-(Cyclohexylamino)-2-hydroxy-1-propanesulfonic acid
Chemical Property:
- Appearance/Colour:white powder
- Melting Point:270-274 °C
- Refractive Index:1.538
- PKA:9.6(at 25℃)
- PSA：95.01000
- Density:1.29 g/cm3
- LogP:1.62910
- Storage Temp.:Sealed in dry,Room Temperature
- Solubility.:H2O: 0.1 g/mL, clear, colorless
- Water Solubility.:Soluble in water (10 g+ 90 ml).
- XLogP3:-2.4
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:5
- Rotatable Bond Count:5
- Exact Mass:237.10347926
- Heavy Atom Count:15
- Complexity:266
- Purity/Quality:
-
99% *data from raw suppliers
3-(Cyclohexylamino)-2-hydroxy-1-propanesulfonicAcid *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xn, 
Xi
- Hazard Codes:Xi,Xn
- Statements:
20/21/22-36/37/38
- Safety Statements:
22-24/25-36-26
- MSDS Files:
-
SDS file from LookChem
Total 1 MSDS from other Authors
Useful:
- Chemical Classes:Other Uses -> Biological Buffers
- Canonical SMILES:C1CCC(CC1)NCC(CS(=O)(=O)O)O
-
Description
CAPSO is a useful secondary standard buffer. Second dissociation constant pK2 value of CAPSO has been measured. Useful pH range for CAPSO is 8.9 - 10.3.CAPSO is a biological and zwitterionic buffer commonly categorized as a Good's buffers. CAPSO has many applications some of which include immunoblotting and westerns. Additionally, CAPSO is used in the electrotransfer of proteins to PVDF or nitrocellulose membranes. CAPS buffer has very low metal-binding constants and are, therefore, particularly suited to investigate metal-dependent enzymes. CAPSO a very water soluble buffering reagent with an optimum buffering pH of 10.4 and minimal reactivity with enzymes or proteins with minimal salt effects.
-
Uses
CAPSO was used as biological buffer in the following studies:To maintain pH 9 during water leach test for the analysis of high-carbon coal fly ash-soil mixtures.Chemiluminescent in situ hybridization using soybean peroxidase-labeled peptide nucleic acid (PNA) probes. Preparation of planar bilayer lipid membranes.It may be employed as buffer for the electrophoretic analyses in non-denaturing gels, to investigate macromolecular self-association of ADP-ribosyltransferase protein in solution. CAPSO is used in various biological applications such as electrophoresis. Specific applications include buffers for protein separations and diagnostic reagent production. Also used as biological buffer in the following studies, to maintain pH 9 during water leach test for the analysis of high-carbon coal fly ash-soil mixtures, chemiluminescent in situ hybridization using soybean peroxidase-labeled peptide nucleic acid (PNA) probes, preparation of planar bilayer lipid membranes.
