7-(1H-Imidazol-1-yl)-5,6,7,8-tetrahydro-2-naphthalenecarboxylic acid

Base Information

Chemical Name:7-(1H-Imidazol-1-yl)-5,6,7,8-tetrahydro-2-naphthalenecarboxylic acid
CAS No.:89781-77-1
Molecular Formula:C₁₄H₁₄N₂O₂
Molecular Weight:242.277
Hs Code.:
DSSTox Substance ID:DTXSID001008970

Synonyms:BRN 4754914;2-Naphthalenecarboxylic acid, 5,6,7,8-tetrahydro-7-(1H-imidazol-1-yl)-;7-(1H-Imidazol-1-yl)-5,6,7,8-tetrahydro-2-naphthalenecarboxylic acid;89781-77-1;SCHEMBL9812566;DTXSID001008970;LS-94530;7-(1H-Imidazol-1-yl)-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid

Suppliers and Price of 7-(1H-Imidazol-1-yl)-5,6,7,8-tetrahydro-2-naphthalenecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7-(1H-Imidazol-1-yl)-5,6,7,8-tetrahydro-2-naphthalenecarboxylic acid

Chemical Property:

Vapor Pressure:2.82E-11mmHg at 25°C
Boiling Point:511.3°Cat760mmHg
Flash Point:263°C
Density:1.32g/cm³
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:242.105527694
Heavy Atom Count:18
Complexity:321

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(CC1N3C=CN=C3)C=C(C=C2)C(=O)O

Technology Process of 7-(1H-Imidazol-1-yl)-5,6,7,8-tetrahydro-2-naphthalenecarboxylic acid

There total 3 articles about 7-(1H-Imidazol-1-yl)-5,6,7,8-tetrahydro-2-naphthalenecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 89781-55-5
5,6-dihydro-7-(1H-imidazol-1-yl)-2-naphthalenecarboxylic acid

: 89781-77-1
(+/-)-5,6,7,8-tetrahydro-7-(1H-imidazol-1-yl)-2-naphthalenecarboxylic acid

Guidance literature:: With hydrogenchloride; hydrogen; acetic acid; palladium on activated charcoal; In ethanol; for 12h; under 2585.7 Torr; Ambient temperature;
DOI:10.1016/0223-5234(91)90103-T

Reference yield:

: 85929-03-9
2-(1-imidazolyl)-1,2,3,4-tetrahydro-7-carboxy-1-naphthalenol

: 89781-77-1
(+/-)-5,6,7,8-tetrahydro-7-(1H-imidazol-1-yl)-2-naphthalenecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / conc. H₂SO₄ / acetic acid / 4 h / 100 °C

2: 66 percent / H₂, AcOH, conc. aq. HCl / 10percent Pd/C / aq. ethanol / 12 h / 2585.7 Torr / Ambient temperature

With hydrogenchloride; sulfuric acid; hydrogen; acetic acid; palladium on activated charcoal; In ethanol; acetic acid;
DOI:10.1016/0223-5234(91)90103-T