Piperidine, 1-[[1-[(2-amino-4-pyridinyl)methyl]-4-piperidinyl]carbonyl]-4-[3-(cyclohex ylmethyl)-5-fluoro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl]-

Base Information

Chemical Name:Piperidine, 1-[[1-[(2-amino-4-pyridinyl)methyl]-4-piperidinyl]carbonyl]-4-[3-(cyclohex ylmethyl)-5-fluoro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl]-
CAS No.:633310-95-9
Molecular Formula:C₃₁H₄₁FN₆O₂
Molecular Weight:548.704
Hs Code.:

Piperidine,
1-[[1-[(2-amino-4-pyridinyl)methyl]-4-piperidinyl]carbonyl]-4-[3-(cyclohex
ylmethyl)-5-fluoro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl]-

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Piperidine, 1-[[1-[(2-amino-4-pyridinyl)methyl]-4-piperidinyl]carbonyl]-4-[3-(cyclohex ylmethyl)-5-fluoro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl]-

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Technology Process of Piperidine, 1-[[1-[(2-amino-4-pyridinyl)methyl]-4-piperidinyl]carbonyl]-4-[3-(cyclohex ylmethyl)-5-fluoro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl]-

There total 6 articles about Piperidine, 1-[[1-[(2-amino-4-pyridinyl)methyl]-4-piperidinyl]carbonyl]-4-[3-(cyclohex ylmethyl)-5-fluoro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1469924-76-2
C₄₁H₅₇FN₆O₆

: 633310-95-9
C₃₁H₄₁FN₆O₂

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃;
DOI:10.1016/j.bmcl.2013.08.012

Reference yield:

: 1469924-45-5
C₂₂H₃₀FN₃O₃

: 633310-95-9
C₃₁H₄₁FN₆O₂

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / water / Reflux

2: dmap; HATU / N,N-dimethyl-formamide

3: hydrogenchloride / 1,4-dioxane / 20 °C

With hydrogenchloride; dmap; HATU; sodium hydroxide; In 1,4-dioxane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2013.08.012

Reference yield:

: 1469924-58-0
C₁₉H₂₆FN₃O

: 633310-95-9
C₃₁H₄₁FN₆O₂

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; HATU / N,N-dimethyl-formamide

2: hydrogenchloride / 1,4-dioxane / 20 °C

With hydrogenchloride; dmap; HATU; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2013.08.012