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BCECF-acetoxymethyl

Base Information
  • Chemical Name:BCECF-acetoxymethyl
  • CAS No.:117464-70-7
  • Molecular Formula:C40H36 O19
  • Molecular Weight:880.75
  • Hs Code.:
  • European Community (EC) Number:601-479-4
  • DSSTox Substance ID:DTXSID90922429
  • Wikidata:Q72444570
  • Mol file:117464-70-7.mol
BCECF-acetoxymethyl

Synonyms:2',7'-bis-(2-carboxyethyl)-5(6)-carboxyfluorescein acetoxymethyl ester;2',7'-CCAE;BCECF-AM;bis(carboxyethyl)carboxyfluorescein acetoxymethyl ester

Suppliers and Price of BCECF-acetoxymethyl
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • BCECF/AM
  • 1mg
  • $ 395.00
  • TRC
  • BCECF/AM
  • 1mg
  • $ 220.00
  • Sigma-Aldrich
  • BCECF/AM
  • 1mg
  • $ 143.37
  • Cayman Chemical
  • BCECF-Acetoxymethyl ester ≥95%
  • 1mg
  • $ 88.00
  • Cayman Chemical
  • BCECF-Acetoxymethyl ester ≥95%
  • 5mg
  • $ 396.00
  • Cayman Chemical
  • BCECF-Acetoxymethyl ester ≥95%
  • 25mg
  • $ 1540.00
  • Biosynth Carbosynth
  • 2',7'-bis(2-Carboxyethyl)-5(6)-carboxyfluorescein acetoxymethyl ester Mixed isomers
  • 10 mg
  • $ 2500.00
  • ApexBio Technology
  • BCECF/AM
  • 25mg
  • $ 2053.00
  • ApexBio Technology
  • BCECF/AM
  • 5mg
  • $ 494.00
  • ApexBio Technology
  • BCECF/AM
  • 1mg
  • $ 110.00
Total 20 raw suppliers
Chemical Property of BCECF-acetoxymethyl
Chemical Property:
  • Refractive Index:1.6500 (estimate) 
  • Boiling Point:692.41°C (rough estimate) 
  • Flash Point:85 °C 
  • PSA:264.39000 
  • Density:1.2837 (rough estimate) 
  • LogP:3.72360 
  • Storage Temp.:-20°C 
  • XLogP3:4
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:21
  • Rotatable Bond Count:27
  • Exact Mass:880.20620828
  • Heavy Atom Count:63
  • Complexity:1610
Purity/Quality:

98%,99%, *data from raw suppliers

BCECF/AM *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes:Xi 
  • Statements: 36/37/38 
  • Safety Statements: 22-26-36 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:CC(=O)OCOC1=CC2=C(C=C1CCC(=O)OCOC(=O)C)C3(C4=C(C=C(C=C4)C(=O)OCOC(=O)C)C(=O)O3)C5=C(O2)C=C(C(=C5)CCC(=O)OCOC(=O)C)OCOC(=O)C
  • Description BCECF AM ester is a widely-used fluorescent indicator for estimating intracellular pH. This membrane-permeant compound is modified by intracellular esterases to produce BCECF, a polar fluorescein derivative that is retained by cells. Intracellular BCECF is stable and has an efflux half-life of greater than two hours. Intracellular pH measurements are made by ratio imaging, which involves determining the pH-dependent ratio of emission intensity (detected at 535 nm) when the dye is excited at 490 nm vs. the emission intensity when excited at 440 nm. This approach is amenable to either spectrofluorometry or flow cytometry. BCECF AM can also be used to investigate intracellular changes in other ions, including potassium.
  • Uses Cell-permeable ester of BCECF that, on hydrolysis by cytosolic esterases, yields the intracellularly trapped pH-indicator BCECF. Allows simultaneous recording of cell volume changes and intracellular pH in single osteosarcoma cells.
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