(3,4-DiMethoxybenzyl)-triphenylphosphoniuM chloride

Base Information

• Chemical Name: (3,4-DiMethoxybenzyl)-triphenylphosphoniuM chloride
• CAS No.: 63368-34-3
• Molecular Formula: C27H26O2P.Cl
• Molecular Weight: 448.929
• Mol file: 63368-34-3.mol

Synonyms:3,4-Dimethoxybenzyltriphenylphosphoniumchlorid;(3,4-dimethoxybenzyl)triphenylphosphonium chloride;(3,4-DiMethoxybenzyl)-triphenylphosphonium chloride;3,4-dimethoxybenzyltriphenylphosphonium chloride;

Chemical Property of (3,4-DiMethoxybenzyl)-triphenylphosphoniuM chloride

Chemical Property:

• PSA: 32.05000
• LogP: 2.20190

Purity/Quality:

95%-98% ^*data from raw suppliers

(3,4-Dimethoxybenzyl)triphenylphosphoniumchloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3,4-DiMethoxybenzyl)-triphenylphosphoniuM chloride

There total 5 articles about (3,4-DiMethoxybenzyl)-triphenylphosphoniuM chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

triphenylphosphine (603-35-0) + 4-chloromethyl-1,2-dimethoxy-benzene (7306-46-9) → (3,4-dimethoxybenzyl)triphenylphosphonium chloride (63368-34-3)

Guidance literature:

In acetonitrile; for 12h; Reflux;

DOI:10.1016/j.ejmech.2014.02.051

Reference yield:

(3,4-dimethoxyphenyl)methanol (93-03-8) → (3,4-dimethoxybenzyl)triphenylphosphonium chloride (63368-34-3)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂ / toluene / 0.08 h / Ambient temperature

2: xylene / 22 h / Heating

With thionyl chloride; In toluene; xylene;

DOI:10.1021/jm980572i

Reference yield:

3,4-dimethoxy-benzaldehyde (120-14-9) → (3,4-dimethoxybenzyl)triphenylphosphonium chloride (63368-34-3)

Guidance literature:

Multi-step reaction with 3 steps

1: NaBH₄ / methanol / Ambient temperature

2: SOCl₂ / toluene / 0.08 h / Ambient temperature

3: xylene / 22 h / Heating

With sodium tetrahydroborate; thionyl chloride; In methanol; toluene; xylene;

DOI:10.1021/jm980572i

upstream raw materials:

triphenylphosphine

3,4-dimethoxybenzoic acid chloride

4-chloromethyl-1,2-dimethoxy-benzene

3,4-dimethoxy-benzaldehyde

Downstream raw materials:

7-(3',4'-dimethoxyphenyl)heptanoic acid

3,3',4'-trimethoxystilbene-2-carboxylic acid

(S)-1-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid ethyl ester

trans-2-<3,4-Dimethoxy-styryl>-naphthalin