(3-Methylbenzyl)Triphenylphosphonium Chloride

Base Information

• Chemical Name: (3-Methylbenzyl)Triphenylphosphonium Chloride
• CAS No.: 63368-37-6
• Molecular Formula: C26H24P.Cl
• Molecular Weight: 402.903
• Hs Code.: 2931900090
• European Community (EC) Number: 667-043-0
• DSSTox Substance ID: DTXSID40369264
• Mol file: 63368-37-6.mol

Synonyms:(3-Methylbenzyl)Triphenylphosphonium Chloride;63368-37-6;(3-methylphenyl)methyl-triphenylphosphanium;chloride;3-Methylbenzyltriphenylphosphonium chloride;Aluminumnitrate;SCHEMBL2447879;DTXSID40369264;MFCD00031579;AKOS017345194;(3-Methylbenzyl)triphenylphosphoniumchloride;FT-0604991;FT-0616134;[(3-Methylphenyl)methyl](triphenyl)phosphanium chloride

Chemical Property of (3-Methylbenzyl)Triphenylphosphonium Chloride

Chemical Property:

• Appearance/Colour: WHITE CRYSTALLINE POWDER
• Melting Point: >300℃
• PSA: 13.59000
• LogP: 2.49310
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 402.1304155
• Heavy Atom Count: 28
• Complexity: 380

Purity/Quality:

99% ^*data from raw suppliers

(3-METHYLBENZYL)TRIPHENYLPHOSPHONIUM CHLORIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC=C1)C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[Cl-]

Technology Process of (3-Methylbenzyl)Triphenylphosphonium Chloride

There total 1 articles about (3-Methylbenzyl)Triphenylphosphonium Chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-chloromethyl-3-methyl-benzene (620-19-9) + triphenylphosphine (603-35-0) → (3-methylbenzyl)triphenylphosphonium chloride (63368-37-6)

Guidance literature:

In acetonitrile; for 4.5h; Reflux;

DOI:10.1021/acsmedchemlett.5b00170

Reference yield: 85.0%

Indole-3-carboxaldehyde (487-89-8,1228547-52-1) + (3-methylbenzyl)triphenylphosphonium chloride (63368-37-6) → (E)-3-(3-methylstyryl)-1H-indole

Guidance literature:

(3-methylbenzyl)triphenylphosphonium chloride; With sodium hydride; In toluene; mineral oil; at 20 ℃; for 0.5h;

Indole-3-carboxaldehyde; In toluene; mineral oil; at 80 ℃; for 2h;

DOI:10.1021/acs.orglett.9b01675

Reference yield: 83.0%

(3-methylbenzyl)triphenylphosphonium chloride (63368-37-6) + benzyl alcohol (100-51-6,185532-71-2) → (E)-3-methylstilbene (14064-48-3)

Guidance literature:

With C₃₇H₃₆Cl₂NPRuS₂; potassium tert-butylate; In 1,4-dioxane; at 135 ℃; for 24h; Inert atmosphere;

DOI:10.1039/c8dt04725a

upstream raw materials:

1-chloromethyl-3-methyl-benzene

triphenylphosphine

Downstream raw materials:

trans,trans-1-(m-methylphenyl)-4-phenyl-butadiene

3-Methyl-3'-benzyloxy-4'-methoxystilben

cyclo[2,2-dimethyl-β-alanyl-(2S)-2-hydroxy-4-methylpentanoyl-(2E,5S,6R,7E)-5-hydroxy-6-methyl-8-(3-methylphenyl)-2,7-octadienoyl-3-chloro-O-methyl-D-tyrosyl]

3-Methyl-3'-hydroxy-4'-methoxydibenzyl

Refernces

• 1、 Guan, Xu-Kai,Liu, Guo-Feng,An, Dong,Zhang, Heng,Zhang, Suo-Qin. "Chiral Imidodiphosphoric Acid-Catalyzed Highly Diastereo- and Enantioselective Synthesis of Poly-Substituted 3,4-Dihydro-2 H-pyrans: [4 + 2] Cycloadditions of β,γ-Unsaturated α-Ketoesters and 3-Vinylindoles". supporting information. p. 5438 - 5442. Retrieved 2019/08/01.
• 2、 Lindberg, Gerd,Stensioe, Karl-Erland,Wahlberg, Kerstin. "Synthesis and Photocylization of some 4-(5)Arylethenylimidazoles". . p. 679 - 683. Retrieved 2007/10/02.