3-CHLORO-1-METHYL-1H-PYRAZOLE

Base Information

• Chemical Name: 3-CHLORO-1-METHYL-1H-PYRAZOLE
• CAS No.: 63425-54-7
• Molecular Formula: C4H5ClN2
• Molecular Weight: 116.54900
• Hs Code.: 2933199090
• Mol file: 63425-54-7.mol

Synonyms:3-chloro-1-methylpyrazole;

Chemical Property of 3-CHLORO-1-METHYL-1H-PYRAZOLE

Chemical Property:

• Boiling Point: 159oC
• PKA: -0.27±0.10(Predicted)
• Flash Point: 50oC
• PSA: 17.82000
• Density: 1.26
• LogP: 1.07350
• Storage Temp.: 2-8°C

Purity/Quality:

NLT 98% ^*data from raw suppliers

3-chloro-1-methyl-1H-pyrazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 23-26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-CHLORO-1-METHYL-1H-PYRAZOLE

There total 1 articles about 3-CHLORO-1-METHYL-1H-PYRAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

methyl-1 amino-3 pyrazole (1904-31-0) → 3-chloro-1-methyl-1H-pyrazole (63425-54-7)

Guidance literature:

methyl-1 amino-3 pyrazole; With hydrogenchloride; sodium nitrite; In water; at 0 - 27 ℃; for 0.5h;

With copper(l) chloride; In water; at 60 ℃; for 1h; Reagent/catalyst; Solvent;

Reference yield: 79.0%

3-chloro-1-methyl-1H-pyrazole (63425-54-7) + methyl p-toluene sulfonate (80-48-8) → Toluene-4-sulfonate5-chloro-1,2-dimethyl-2H-pyrazol-1-ium; (50877-48-0)

Guidance literature:

at 120 ℃; for 3h;

Reference yield: 73.0%

3-chloro-1-methyl-1H-pyrazole (63425-54-7) → 3-chloro-1-methyl-4-nitro-1H-pyrazole (299930-70-4)

Guidance literature:

With sulfuric acid; nitric acid; at 27 ℃; for 6h; Time; Cooling with ice;

upstream raw materials:

methyl-1 amino-3 pyrazole

Downstream raw materials:

Toluene-4-sulfonate5-chloro-1,2-dimethyl-2H-pyrazol-1-ium;

3-chloro-1-methyl-4-nitro-1H-pyrazole

Refernces

• 1、 -. "4-Methylsulfonyl-Substituted Piperidine Urea Compounds". Paragraph 0189-0190. . Retrieved 2016/09/26.
• 2、 -. "Pyrazolecarboxylic acid derivatives and plant disease control agent". . . Retrieved 2008/06/13.