3-Methyl-1-phenyl-4-(piperidinomethylene)-2-pyrazolin-5-one

Base Information

Chemical Name:3-Methyl-1-phenyl-4-(piperidinomethylene)-2-pyrazolin-5-one
CAS No.:5496-04-8
Molecular Formula:C16H19N3O
Molecular Weight:269.346
Hs Code.:2933990090
Nikkaji Number:J51.257E
Mol file:5496-04-8.mol

Synonyms:3-Methyl-1-phenyl-4-(piperidinomethylene)-2-pyrazolin-5-one;BRN 0616565;5496-04-8;(4E)-5-methyl-2-phenyl-4-(piperidin-1-ylmethylidene)pyrazol-3-one;2-Pyrazolin-5-one, 3-methyl-1-phenyl-4-(piperidinomethylene)-;LS-128904;SR-01000394328;SR-01000394328-1;5-methyl-2-phenyl-4-[(E)-1-piperidinomethylidene]-2,4-dihydro-3H-pyrazol-3-one

Suppliers and Price of 3-Methyl-1-phenyl-4-(piperidinomethylene)-2-pyrazolin-5-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 3-Methyl-1-phenyl-4-(piperidinomethylene)-2-pyrazolin-5-one

Chemical Property:

Vapor Pressure:7.73E-06mmHg at 25°C
Boiling Point:375.5°Cat760mmHg
Flash Point:180.9°C
PSA：35.91000
Density:1.18g/cm³
LogP:2.21740
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:269.152812238
Heavy Atom Count:20
Complexity:429

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NN(C(=O)C1=CN2CCCCC2)C3=CC=CC=C3
Isomeric SMILES:CC\1=NN(C(=O)/C1=C/N2CCCCC2)C3=CC=CC=C3

Technology Process of 3-Methyl-1-phenyl-4-(piperidinomethylene)-2-pyrazolin-5-one

There total 1 articles about 3-Methyl-1-phenyl-4-(piperidinomethylene)-2-pyrazolin-5-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5496-04-8
1-phenyl-3-methyl-4-piperidinomethylene-5-pyrazolone

Guidance literature:: 3-Methyl-4-thioureidomethylen-1-phenylpyrazolon-5, Piperidin/Dioxan;

Reference yield:

: 151-50-8
potassium cyanide

: 5496-04-8
1-phenyl-3-methyl-4-piperidinomethylene-5-pyrazolone

: 107486-76-0
mononitrile of (1-phenyl-3-methyl-5-oxo-4-pyrazolylidene)succinic acid

: 97227-13-9
potassium salt of the mononitrile of (1-phenyl-3-methyl-5-oxo-4-pyrazolylidene)malonic acid

: 4702-90-3,190086-12-5
1-phenyl-3-methyl-4-(1-phenyl-3-methyl-5-oxo-4-pyrazolylidene)methylene-5-pyrazolone

Guidance literature:: With oxygen; In N,N-dimethyl acetamide; at 80 - 90 ℃; for 8h;

Reference yield:

: 5496-04-8
1-phenyl-3-methyl-4-piperidinomethylene-5-pyrazolone

: 97227-14-0
mononitrile of 1-phenyl-3-methyl-5-oxopyrazolidene-4-malonic acid

Guidance literature:: Multi-step reaction with 3 steps

1: N,N-dimethyl-acetamide / 8 h / 90 °C

2: 60 percent / KCN / N,N-dimethyl-acetamide

3: 60 percent / 5percent aq. H₃PO₄ / H₂O

With potassium cyanide; phosphoric acid; In N,N-dimethyl acetamide; water;