3-Isoxazolecarboxylic acid, 2-[(2S)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-oxo-3-[(phenylmeth yl)thio]propyl]-2,5-dihydro-4-methyl-5-oxo-, ethyl ester

Base Information

Chemical Name:3-Isoxazolecarboxylic acid, 2-[(2S)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-oxo-3-[(phenylmeth yl)thio]propyl]-2,5-dihydro-4-methyl-5-oxo-, ethyl ester
CAS No.:634585-64-1
Molecular Formula:C25H22N2O7S
Molecular Weight:494.525
Hs Code.:

3-Isoxazolecarboxylic acid,
2-[(2S)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-oxo-3-[(phenylmeth
yl)thio]propyl]-2,5-dihydro-4-methyl-5-oxo-, ethyl ester

Synonyms:

Suppliers and Price of 3-Isoxazolecarboxylic acid, 2-[(2S)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-oxo-3-[(phenylmeth yl)thio]propyl]-2,5-dihydro-4-methyl-5-oxo-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-Isoxazolecarboxylic acid, 2-[(2S)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-oxo-3-[(phenylmeth yl)thio]propyl]-2,5-dihydro-4-methyl-5-oxo-, ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Isoxazolecarboxylic acid, 2-[(2S)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-oxo-3-[(phenylmeth yl)thio]propyl]-2,5-dihydro-4-methyl-5-oxo-, ethyl ester

There total 1 articles about 3-Isoxazolecarboxylic acid, 2-[(2S)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-oxo-3-[(phenylmeth yl)thio]propyl]-2,5-dihydro-4-methyl-5-oxo-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 84280-59-1
ethyl 4-methyl-5-oxo-2,5-dihydro-1,2-oxazole-3-carboxylate

: (S)-3-Benzylsulfanyl-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionic acid

: 634585-64-1
(S)-ethyl 2-[3-benzylthio-2-phthalimidopropanoyl]-4-methyl-5-oxo-2,5-dihydroisoxazole-3-carboxylate

Guidance literature:: With dicyclohexyl-carbodiimide; In dichloromethane; N,N-dimethyl-formamide; at 0 - 20 ℃; for 19h;
DOI:10.1071/CH03052

Reference yield: 13.0%

: 634585-64-1
(S)-ethyl 2-[3-benzylthio-2-phthalimidopropanoyl]-4-methyl-5-oxo-2,5-dihydroisoxazole-3-carboxylate

: 3485-84-5,26809-43-8
N-vinylphthalimide

: 634585-69-6
ethyl (S)-5-methyl-2-(2-benzylthio-1-phthalimidoethyl)-oxazole-4-carboxylate

: ethyl (R)-5-methyl-2-(2-benzylthio-1-phthalimidoethyl)-oxazole-4-carboxylate

Guidance literature:: In acetone; at 20 ℃; for 3h; Title compound not separated from byproducts; UV-irradiation;
DOI:10.1071/CH03052

Reference yield:

: 634585-64-1
(S)-ethyl 2-[3-benzylthio-2-phthalimidopropanoyl]-4-methyl-5-oxo-2,5-dihydroisoxazole-3-carboxylate

: 2-((S)-1-Amino-2-benzylsulfanyl-ethyl)-5-methyl-oxazole-4-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: acetone / 3 h / 20 °C / UV-irradiation

2: hydrazine hydrate

With hydrazine hydrate; In acetone;
DOI:10.1071/CH03052