Welcome to LookChem.com Sign In|Join Free
  • or

Encyclopedia

methyl (3S,5R,6R)-3,4,5-triacetyloxy-6-bromanyl-oxane-2-carboxylate

Base Information Edit
  • Chemical Name:methyl (3S,5R,6R)-3,4,5-triacetyloxy-6-bromanyl-oxane-2-carboxylate
  • CAS No.:21085-72-3
  • Molecular Formula:C13H17BrO9
  • Molecular Weight:397.177
  • Hs Code.:29189900
  • European Community (EC) Number:244-203-4
  • Mol file:21085-72-3.mol
methyl (3S,5R,6R)-3,4,5-triacetyloxy-6-bromanyl-oxane-2-carboxylate

Synonyms:21085-72-3;SCHEMBL13830203;A815129;(3S,5R,6R)-3,4,5-triacetyloxy-6-bromo-2-oxanecarboxylic acid methyl ester;methyl (3S,5R,6R)-3,4,5-triacetyloxy-6-bromanyl-oxane-2-carboxylate

Suppliers and Price of methyl (3S,5R,6R)-3,4,5-triacetyloxy-6-bromanyl-oxane-2-carboxylate
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • Acetobromo-a-D-glucuronic Acid, Methyl Ester
  • 2g
  • $ 403.00
  • TRC
  • Acetobromo-α-D-glucuronicAcidMethylEster(contains2%CaCO3)
  • 5g
  • $ 275.00
  • SynQuest Laboratories
  • Acetobromo-alpha-D-glucuronicacid,methylester 95.0%
  • 25 g
  • $ 832.00
  • SynQuest Laboratories
  • Acetobromo-alpha-D-glucuronicacid,methylester 95.0%
  • 1 g
  • $ 56.00
  • SynQuest Laboratories
  • Acetobromo-alpha-D-glucuronicacid,methylester 95.0%
  • 5 g
  • $ 200.00
  • Sigma-Aldrich
  • Acetobromo-α-D-glucuronic acid methyl ester ≥93%
  • 1g
  • $ 213.00
  • Sigma-Aldrich
  • Acetobromo-α-D-glucuronic acid methyl ester ≥93%
  • 5g
  • $ 729.00
  • Medical Isotopes, Inc.
  • Acetobromo-α-D-glucuronic acid methyl ester
  • 2 g
  • $ 890.00
  • Matrix Scientific
  • (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)-tetrahydro-2H-pyran-3,4,5-triyl triacetate 95+%
  • 5g
  • $ 180.00
  • Matrix Scientific
  • (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)-tetrahydro-2H-pyran-3,4,5-triyl triacetate 95+%
  • 1g
  • $ 55.00
Total 109 raw suppliers
Chemical Property of methyl (3S,5R,6R)-3,4,5-triacetyloxy-6-bromanyl-oxane-2-carboxylate Edit
Chemical Property:
  • Appearance/Colour:White Crystalline Solid 
  • Vapor Pressure:3.02E-06mmHg at 25°C 
  • Melting Point:80-110°C(lit.) 
  • Refractive Index:1.504 
  • Boiling Point:388.6 °C at 760 mmHg 
  • Flash Point:188.8 °C 
  • PSA:114.43000 
  • Density:1.52g/cm3 
  • LogP:0.07430 
  • Storage Temp.:−20°C 
  • Solubility.:Acetonitrile (Slightly), Chloroform (Slightly, Heated, Sonicated), Dichlorometha 
  • XLogP3:0.6
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:9
  • Rotatable Bond Count:8
  • Exact Mass:396.00559
  • Heavy Atom Count:23
  • Complexity:492
Purity/Quality:

98% *data from raw suppliers

Acetobromo-a-D-glucuronic Acid, Methyl Ester *data from reagent suppliers

Safty Information:
  • Pictogram(s): IrritantXi 
  • Hazard Codes:Xi 
  • Statements: 36/37/38 
  • Safety Statements: 22-24/25 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:CC(=O)OC1C(C(OC(C1OC(=O)C)Br)C(=O)OC)OC(=O)C
  • Isomeric SMILES:CC(=O)O[C@H]1[C@H](OC([C@H](C1OC(=O)C)OC(=O)C)C(=O)OC)Br
  • Uses Acetobromo-α-D-glucuronic acid methyl ester is used for the synthesis of HMR1098-S-glucuronide methyl ester, a new K-ATP-blocking agent being developed as a drug for prevention of sudden cardiac death. Acetobromo-α-D-glucuronic acid methyl ester is used for the synthesis of water-soluble glucuronide derivatives of Camptothecin, which is used for cancer prodrug monotherapy and antibody-directed enzyme prodrug therapy (ADEPT). Acetobromo-α-D-glucuronic acid methyl ester is used for the synthesis of glucuronide prodrug compounds of Janus kinase (JAK) inhibitor tofacitinib, which could be cleaved by β-glucuronidase enzymes such as those produced by the microbiome in the gastrointestinal tract, thereby increasing levels of tofacitinib at the site of gastrointestinal inflammation and limiting the systemic exposure of tofacitinib when treating localized inflammatory diseases.
Technology Process of methyl (3S,5R,6R)-3,4,5-triacetyloxy-6-bromanyl-oxane-2-carboxylate

There total 29 articles about methyl (3S,5R,6R)-3,4,5-triacetyloxy-6-bromanyl-oxane-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Post RFQ for Price