diethyl (1R,2S)-4-methylidenecyclopentane-1,2-dicarboxylate

Base Information

Chemical Name:diethyl (1R,2S)-4-methylidenecyclopentane-1,2-dicarboxylate
CAS No.:63649-26-3
Molecular Formula:C12H18O4
Molecular Weight:226.273
Hs Code.:
DSSTox Substance ID:DTXSID70426253
Wikidata:Q82239203

Synonyms:CTK1I6188;63649-26-3;DTXSID70426253

Suppliers and Price of diethyl (1R,2S)-4-methylidenecyclopentane-1,2-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of diethyl (1R,2S)-4-methylidenecyclopentane-1,2-dicarboxylate

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:226.12050905
Heavy Atom Count:16
Complexity:267

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1CC(=C)CC1C(=O)OCC
Isomeric SMILES:CCOC(=O)[C@@H]1CC(=C)C[C@@H]1C(=O)OCC

Technology Process of diethyl (1R,2S)-4-methylidenecyclopentane-1,2-dicarboxylate

There total 10 articles about diethyl (1R,2S)-4-methylidenecyclopentane-1,2-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.2%

: 6142-73-0
methylene cyclopropane

: 141-05-9
Diethyl maleate

: 63649-26-3
(1S,2R)-4-Methylene-cyclopentane-1,2-dicarboxylic acid diethyl ester

: 63649-25-2,63649-26-3
(1S,2S)-4-Methylene-cyclopentane-1,2-dicarboxylic acid diethyl ester

: 80137-90-2
(1R,2R)-4-(4,5-Bis-ethoxycarbonyl-2-methylene-pentyl)-cyclohex-4-ene-1,2-dicarboxylic acid diethyl ester

: 80137-90-2
(1S,2R)-4-(4,5-Bis-ethoxycarbonyl-2-methylene-pentyl)-cyclohex-4-ene-1,2-dicarboxylic acid diethyl ester

Guidance literature:: With diethyl(ethoxy)aluminum; tris(1-methylethyl)phosphine; palladium(II) acetylacetonate; In toluene; at 100 ℃; for 16h; Yield given. Further byproducts given. Title compound not separated from byproducts;

Reference yield: 58.2%

: 6142-73-0
methylene cyclopropane

: 141-05-9
Diethyl maleate

: 63649-26-3
(1S,2R)-4-Methylene-cyclopentane-1,2-dicarboxylic acid diethyl ester

: 63649-25-2,63649-26-3
(1S,2S)-4-Methylene-cyclopentane-1,2-dicarboxylic acid diethyl ester

: 80137-90-2
(1R,2R)-4-(4,5-Bis-ethoxycarbonyl-2-methylene-pentyl)-cyclohex-4-ene-1,2-dicarboxylic acid diethyl ester

: 80137-90-2
(1S,2R)-4-(4,5-Bis-ethoxycarbonyl-2-methylene-pentyl)-cyclohex-4-ene-1,2-dicarboxylic acid diethyl ester

Guidance literature:: With diethyl(ethoxy)aluminum; tris(1-methylethyl)phosphine; palladium(II) acetylacetonate; In toluene; at 100 ℃; for 16h; Yield given. Further byproducts given. Title compound not separated from byproducts;

Reference yield:

: 6142-73-0
methylene cyclopropane

: 141-05-9
Diethyl maleate

: 63649-26-3
(1S,2R)-4-Methylene-cyclopentane-1,2-dicarboxylic acid diethyl ester

: 80137-88-8,80137-89-9
(1S,2S)-4-(2-Methyl-allyl)-cyclohex-4-ene-1,2-dicarboxylic acid diethyl ester

: 80137-90-2
(1R,2R)-4-(4,5-Bis-ethoxycarbonyl-2-methylene-pentyl)-cyclohex-4-ene-1,2-dicarboxylic acid diethyl ester

: 80137-90-2
(1S,2R)-4-(4,5-Bis-ethoxycarbonyl-2-methylene-pentyl)-cyclohex-4-ene-1,2-dicarboxylic acid diethyl ester

Guidance literature:: With tris(1-methylethyl)phosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In toluene; at 100 ℃; for 16h; Yield given. Further byproducts given. Yields of byproduct given;