4-Cyclopentene-1,3-diol, 1-methyl-, 3-acetate, (1S,3R)- (9CI)

Base Information

Chemical Name:4-Cyclopentene-1,3-diol, 1-methyl-, 3-acetate, (1S,3R)- (9CI)
CAS No.:639467-33-7
Molecular Formula:C8H12O3
Molecular Weight:156.17900
Hs Code.:
Mol file:639467-33-7.mol

Synonyms:Acetic acid (1R,4S)-4-hydroxy-4-methyl-cyclopent-2-enyl ester;(1R,4S)-4-Hydroxy-4-methyl-2-cyclopenten-1-yl acetate;

Suppliers and Price of 4-Cyclopentene-1,3-diol, 1-methyl-, 3-acetate, (1S,3R)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-Cyclopentene-1,3-diol, 1-methyl-, 3-acetate, (1S,3R)- (9CI)

Chemical Property:

PSA：46.53000
LogP:0.62900

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 4-Cyclopentene-1,3-diol, 1-methyl-, 3-acetate, (1S,3R)- (9CI)

There total 7 articles about 4-Cyclopentene-1,3-diol, 1-methyl-, 3-acetate, (1S,3R)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.62%

: 108-24-7
acetic anhydride

: 639467-32-6
(1S,4R)-1-methylcyclopent-2-ene-1,4-diol

: 639467-33-7
(1R,4S)-4-hydroxy-4-methyl-2-cyclopenten-1-yl acetate

Guidance literature:: With pyridine; In dichloromethane; at 20 ℃;
DOI:10.1021/jo030238g

Reference yield: 58.77%

: 639467-32-6
(1S,4R)-1-methylcyclopent-2-ene-1,4-diol

: 639467-33-7
(1R,4S)-4-hydroxy-4-methyl-2-cyclopenten-1-yl acetate

Guidance literature:: With acetic anhydride; sodium hydrogencarbonate; dmap; In tetrahydrofuran; ethyl acetate;

Reference yield:

: 61305-35-9
(R)-4-((tert-butyldimethylsilyl)oxy)cyclopent-2-enone

: 639467-33-7
(1R,4S)-4-hydroxy-4-methyl-2-cyclopenten-1-yl acetate

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / diethyl ether / 3 h / -40 °C

2: 62.3 percent / Bu₄NF / tetrahydrofuran / 3 h / 20 °C

3: 77.62 percent / pyridine / CH₂Cl₂ / 20 °C

With pyridine; tetrabutyl ammonium fluoride; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/jo030238g