Butamirate citrate

Base Information

• Chemical Name: Butamirate citrate
• CAS No.: 18109-81-4
• Molecular Formula: C24H37NO10
• Molecular Weight: 499.558
• European Community (EC) Number: 242-006-8
• UNII: 67HP51L98R
• DSSTox Substance ID: DTXSID0046270
• Wikidata: Q27264132
• NCI Thesaurus Code: C142976
• ChEMBL ID: CHEMBL2106133
• Mol file: 18109-81-4.mol

Synonyms:2-(2-(diethylamino)ethoxy)ethyl-2-phenylbutyrate citrate;2-(2-diethylaminoethoxy)ethyl-2-phenylbutamyrate dihydrogen citrate;butamirate;butamirate citrate;butamyrate citrate;HH 197;Sinecod

Chemical Property of Butamirate citrate

Chemical Property:

• Appearance/Colour: White solid
• Vapor Pressure: 1.99E-06mmHg at 25°C
• Melting Point: 66-68 °C
• Boiling Point: 394.4 °C at 760 mmHg
• Flash Point: 192.3 °C
• PSA: 170.90000
• LogP: 1.83330
• Storage Temp.: Hygroscopic, Refrigerator, Under Inert Atmosphere
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 17
• Exact Mass: 499.24174638
• Heavy Atom Count: 35
• Complexity: 513

Purity/Quality:

Butamirate Citrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C1=CC=CC=C1)C(=O)OCCOCCN(CC)CC.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
• Recent ClinicalTrials: A Study of Butamirate Citrate Syrup Versus (vs) Sinecod Syrup (Vanilla) in Adult Healthy Study Volunteers
• Recent EU Clinical Trials: Prospective, controlled, randomized, investigator-masked, mul-ticenter, phase III trial to demonstrate the efficacy and safety of Brimonidine UD
• Uses: Anxiolytic, Muscle Relaxant A novel antitussive drug. Butamirate Citrate is a novel antitussive drug. Cough suppressant. Syrup is used for the symptomatic treatment of non-productive (dry) cough.
• Therapeutic Function: Antitussive

Technology Process of Butamirate citrate

There total 1 articles about Butamirate citrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ butamirate citrate (18109-81-4)

Guidance literature:

α-Phenylbuttersaeurechlorid, Diethylaminoethoxyethanol, Zitronensaeure;