8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

Base Information

Chemical Name:8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
CAS No.:64368-85-0
Molecular Formula:C12H13FN2
Molecular Weight:204.247
Hs Code.:2933990090
Mol file:64368-85-0.mol

Synonyms:8-fluoro-2,3,4,5-tetrahydro-2-methyl-1H-pyrido[4,3-b]indole;8-fluoro-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole;8-fluoro-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indole;8-fluoro-2,3,4,5-tetrahydropyrido[4,3-b]indole;8-Fluoro-1H,2H,3H,4H,5H-Pyrido[4,3-B]Indole;

Suppliers and Price of 8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
100mg
$ 130.00

Matrix Scientific
8-Fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
500mg
$ 252.00

Crysdot
8-Fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 95+%
1g
$ 297.00

ChemBridge Corporation
8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 95%
1 g
$ 235.00

American Custom Chemicals Corporation
8-FLUORO-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE 95.00%
5MG
$ 503.71

AK Scientific
8-Fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
500mg
$ 390.00

Total 7 raw suppliers

Chemical Property of 8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

Chemical Property:

PSA：19.03000
LogP:2.23280

Purity/Quality:

98%min ^*data from raw suppliers

8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

There total 7 articles about 8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 1445-73-4
1-Methyl-4-piperidone

: 823-85-8
4-fluorophenyhydrazine hydrochloride

: 64368-85-0
8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

Guidance literature:: 4-fluorophenyhydrazine hydrochloride; With sulfuric acid; In 1,4-dioxane; at 20 ℃; for 0.0833333h;

1-Methyl-4-piperidone; In 1,4-dioxane; at 80 ℃; for 2h;

With potassium hydroxide; In water; pH=10; Product distribution / selectivity;

Reference yield:

: 1296771-12-4
CF₃O₃S^(1-)*C₁₂H₁₀FN₂⁽¹⁺⁾

: 64368-85-0
8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

Guidance literature:: With sodium tetrahydroborate; In methanol; water; at 20 - 100 ℃; Inert atmosphere;
DOI:10.1021/ol2008268

Reference yield:

: 923293-16-7
4-fluoro-2-pyridin-3-ylphenylamine

: 64368-85-0
8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

Guidance literature:: Multi-step reaction with 4 steps

1.1: acetic acid; sodium nitrite / water / 1.5 h / 0 °C / Inert atmosphere

1.2: 0 - 20 °C / Inert atmosphere

2.1: dichloromethane / 20 °C / Inert atmosphere

3.1: ruthenium trichloride hydrate / Isopropyl acetate / 15 h / 80 °C / Inert atmosphere

4.1: sodium tetrahydroborate / methanol; water / 20 - 100 °C / Inert atmosphere

With sodium tetrahydroborate; ruthenium trichloride hydrate; acetic acid; sodium nitrite; In methanol; dichloromethane; Isopropyl acetate; water;
DOI:10.1021/ol2008268