5-(2,4,5-Triethoxybenzyl)-2,4-thiazolidinedione

Base Information

Chemical Name:5-(2,4,5-Triethoxybenzyl)-2,4-thiazolidinedione
CAS No.:79525-01-2
Molecular Formula:C₁₆H₂₁NO₅S
Molecular Weight:339.412
Hs Code.:
DSSTox Substance ID:DTXSID401000566
Nikkaji Number:J59.620E

Synonyms:BRN 5769524;5-(2,4,5-Triethoxybenzyl)-2,4-thiazolidinedione;2,4-Thiazolidinedione, 5-(2,4,5-triethoxybenzyl)-;2,4-Thiazolidinedione, 5-((2,4,5-triethoxyphenyl)methyl)-;79525-01-2;SCHEMBL11163531;DTXSID401000566;LS-151348;4-Hydroxy-5-[(2,4,5-triethoxyphenyl)methyl]-1,3-thiazol-2(5H)-one

Suppliers and Price of 5-(2,4,5-Triethoxybenzyl)-2,4-thiazolidinedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 5-(2,4,5-Triethoxybenzyl)-2,4-thiazolidinedione

Chemical Property:

Vapor Pressure:2.12E-10mmHg at 25°C
Boiling Point:507°Cat760mmHg
Flash Point:260.4°C
Density:1.225g/cm³
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:339.11404394
Heavy Atom Count:23
Complexity:419

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=CC(=C(C=C1CC2C(=O)NC(=O)S2)OCC)OCC

Technology Process of 5-(2,4,5-Triethoxybenzyl)-2,4-thiazolidinedione

There total 3 articles about 5-(2,4,5-Triethoxybenzyl)-2,4-thiazolidinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-Chloro-3-oxo-2-(2,4,5-triethoxy-benzyl)-butyric acid ethyl ester

: 79525-01-2
5-(2,4,5-triethoxybenzyl)thiazolidine-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 2N NaOH / ethanol / 0.5 h / Ambient temperature

2: 2.) 1N HCl / 1.) sulfolane, 110 deg C, 8 h, 2.) sulfolane, reflux, 8 h

With hydrogenchloride; sodium hydroxide; In ethanol;
DOI:10.1248/cpb.31.560

Reference yield:

: 85010-91-9
ethyl 2-chloro-3-(2,4,5-triethoxyphenyl)propionic acid

: 17356-08-0
thiourea

: 79525-01-2
5-(2,4,5-triethoxybenzyl)thiazolidine-2,4-dione

Guidance literature:: With hydrogenchloride; Yield given. Multistep reaction; 1.) sulfolane, 110 deg C, 8 h, 2.) sulfolane, reflux, 8 h;
DOI:10.1248/cpb.31.560

Reference yield:

: 85003-59-4
3,4,6-triethoxybenzyl chloride

: 79525-01-2
5-(2,4,5-triethoxybenzyl)thiazolidine-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH; 2.) KOH / 1.) DMF, 70 deg C, 2 h; 2.) EtOH, ice cooling, 20 min

2: 2.) 2N HCl / 1.) sulfolane, 120 deg C, 10 h; 2.) sulfolane, 100 deg C, 8 h

With hydrogenchloride; potassium hydroxide; sodium hydride;
DOI:10.1248/cpb.30.3580