(4R,11R,18R)-11-Isopropyl-4,7,18-trimethyl-6-oxa-13,20-dithia-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1(5,8).1(12,15)]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione

Base Information

Chemical Name:(4R,11R,18R)-11-Isopropyl-4,7,18-trimethyl-6-oxa-13,20-dithia-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1(5,8).1(12,15)]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione
CAS No.:176666-84-5
Molecular Formula:C21H24N6O4S2
Molecular Weight:488.5831
Hs Code.:

(4R,11R,18R)-11-Isopropyl-4,7,18-trimethyl-6-oxa-13,20-dithia-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1(5,8).1(12,15)]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione

Synonyms:

Suppliers and Price of (4R,11R,18R)-11-Isopropyl-4,7,18-trimethyl-6-oxa-13,20-dithia-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1(5,8).1(12,15)]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (4R,11R,18R)-11-Isopropyl-4,7,18-trimethyl-6-oxa-13,20-dithia-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1(5,8).1(12,15)]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione

Chemical Property:

Vapor Pressure:9.48E-31mmHg at 25°C
Boiling Point:870.5°Cat760mmHg
Flash Point:480.2°C
Density:1.275g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (4R,11R,18R)-11-Isopropyl-4,7,18-trimethyl-6-oxa-13,20-dithia-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1(5,8).1(12,15)]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione

There total 60 articles about (4R,11R,18R)-11-Isopropyl-4,7,18-trimethyl-6-oxa-13,20-dithia-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1(5,8).1(12,15)]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1'(R)-2-(1-{[1'(R)-2-(1-{[2-(1-aminoethyl)thiazole-4-carbonyl]amino}ethyl)-5-methyloxazole-4-carbonyl]amino}-1'(R)-2-methylpropyl)thiazole-4-carboxylic acid hydrochloride

: 176666-84-5
dendroamide A

Guidance literature:: With pentafluorophenyl diphenyl-phosphinate; N-ethyl-N,N-diisopropylamine; In acetonitrile;

Reference yield: 66.0%

: 1236201-84-5
C₁₁H₁₆N₂O₅

: 112495-90-6
(R)-2-(1-((tert-butoxycarbonyl)amino)ethyl)thiazole-4-carboxylic acid

: 126300-99-0
2-[(R)-1-(t-butoxycarbonylamino)-2-methylpropyl]thiazole-4-carboxylic acid

: 176666-84-5
dendroamide A

Guidance literature:: C₁₁H₁₆N₂O₅; With 6-chloro-3-((dimethylamino)(dimethyliminio)methyl)-1H-benzo[d][1,2,3]triazol-3-ium-1-olatehexafluorophosphate(V); N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 12h; Kaiser oxime resin

With acetic anhydride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 0.5h; Kaiser oxime resin

(R)-2-(1-((tert-butoxycarbonyl)amino)ethyl)thiazole-4-carboxylic acid; 2-[(R)-1-(t-butoxycarbonylamino)-2-methylpropyl]thiazole-4-carboxylic acid; Further stages;
DOI:10.1021/co400071y

Reference yield: 57.0%

: 847364-25-4
2-((R)-1-{[2-((R)-1-{[2-((R)-1-Amino-2-methyl-propyl)-thiazole-4-carbonyl]-amino}-ethyl)-thiazole-4-carbonyl]-amino}-ethyl)-5-methyl-oxazole-4-carboxylic acid

: 176666-84-5
dendroamide A

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 48h;
DOI:10.3987/COM-04-10233