4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3-iodo-

Base Information

Chemical Name:4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3-iodo-
CAS No.:645387-26-4
Molecular Formula:C17H13IO4
Molecular Weight:408.192
Hs Code.:
DSSTox Substance ID:DTXSID30461802
Nikkaji Number:J1.968.024J
Wikidata:Q82286219

Synonyms:645387-26-4;4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3-iodo-;2-(3,4-dimethoxyphenyl)-3-iodo-4H-chromen-4-one;DTXSID30461802

Suppliers and Price of 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3-iodo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3-iodo-

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:407.98586
Heavy Atom Count:22
Complexity:462

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C2=C(C(=O)C3=CC=CC=C3O2)I)OC

Technology Process of 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3-iodo-

There total 4 articles about 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3-iodo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 79140-20-8,19152-36-4
2'-hydroxy-3,4-dimethoxychalcone

: 645387-26-4
2-(3,4-dimethoxyphenyl)-3-iodo-4H-4-chromenone

Guidance literature:: With iodine; In dimethyl sulfoxide; at 190 ℃; for 12h; Reflux;
DOI:10.1016/j.bmc.2011.04.010

Reference yield:

: 118-93-4,104809-67-8
o-hydroxyacetophenone

: 645387-26-4
2-(3,4-dimethoxyphenyl)-3-iodo-4H-4-chromenone

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / Inert atmosphere

1.2: 16.25 h / 20 °C

2.1: iodine / dimethyl sulfoxide / 12 h / 190 °C / Reflux

With iodine; sodium hydride; In tetrahydrofuran; dimethyl sulfoxide; mineral oil; 1.2: Aldol condensation;
DOI:10.1016/j.bmc.2011.04.010

Reference yield:

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 645387-26-4
2-(3,4-dimethoxyphenyl)-3-iodo-4H-4-chromenone

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / Inert atmosphere

1.2: 16.25 h / 20 °C

2.1: iodine / dimethyl sulfoxide / 12 h / 190 °C / Reflux

With iodine; sodium hydride; In tetrahydrofuran; dimethyl sulfoxide; mineral oil; 1.2: Aldol condensation;
DOI:10.1016/j.bmc.2011.04.010