{1-[(2-Fluorophenyl)methyl]-1H-pyrrol-2-yl}methanol

Base Information

Chemical Name:{1-[(2-Fluorophenyl)methyl]-1H-pyrrol-2-yl}methanol
CAS No.:64630-48-4
Molecular Formula:C12H12FNO
Molecular Weight:205.22800
Hs Code.:
DSSTox Substance ID:DTXSID90543057
Wikidata:Q82419888

Synonyms:64630-48-4;[1-(2-Fluoro-benzyl)-1H-pyrrol-2-yl]-methanol;{1-[(2-Fluorophenyl)methyl]-1H-pyrrol-2-yl}methanol;SCHEMBL11740436;DTXSID90543057;AKOS015744313

Suppliers and Price of {1-[(2-Fluorophenyl)methyl]-1H-pyrrol-2-yl}methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of {1-[(2-Fluorophenyl)methyl]-1H-pyrrol-2-yl}methanol

Chemical Property:

PSA：25.16000
LogP:2.16780
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:205.090292168
Heavy Atom Count:15
Complexity:200

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CN2C=CC=C2CO)F

Technology Process of {1-[(2-Fluorophenyl)methyl]-1H-pyrrol-2-yl}methanol

There total 3 articles about {1-[(2-Fluorophenyl)methyl]-1H-pyrrol-2-yl}methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 63880-57-9
1-[(2-fluorophenyl)methyl]pyrrole-2-carboxaldehyde

: 64630-48-4
<1-(o-fluorobenzyl)pyrryl>methanol

Guidance literature:: With sodium tetrahydroborate; In isopropyl alcohol; at 80 ℃; for 20h;
DOI:10.1002/jhet.5570220429

Reference yield:

: 63880-21-7
1-(2-fluorobenzyl)-1H-pyrrole

: 64630-48-4
<1-(o-fluorobenzyl)pyrryl>methanol

Guidance literature:: Multi-step reaction with 2 steps

1: 1) POCl₃ / 1) room temp., 15 min.; 2) 1,2-dichloroethane

2: 95 percent / NaBH₄ / propan-2-ol / 20 h / 80 °C

With sodium tetrahydroborate; trichlorophosphate; In isopropyl alcohol;
DOI:10.1002/jhet.5570220429