2-Amino-1-[3-(trifluoromethyl)phenyl]ethanone

Base Information

Chemical Name:2-Amino-1-[3-(trifluoromethyl)phenyl]ethanone
CAS No.:64748-87-4
Molecular Formula:C₉H₈F₃NO
Molecular Weight:203.164
Hs Code.:
DSSTox Substance ID:DTXSID20538436
Wikidata:Q82413829

Synonyms:64748-87-4;2-amino-1-[3-(trifluoromethyl)phenyl]ethanone;2-amino-1-(3-(trifluoromethyl)phenyl)ethanone;2-Amino-1-[3-(trifluoromethyl)phenyl]ethan-1-one;2-Amino-1-(3-(trifluoromethyl)phenyl)ethan-1-one;SCHEMBL311526;DTXSID20538436;CS-0289868;2-Amino-1-(3-trifluoromethyl-phenyl)-ethanone;EN300-151220;A1-05689

Suppliers and Price of 2-Amino-1-[3-(trifluoromethyl)phenyl]ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Amino-1-[3-(trifluoromethyl)phenyl]ethanone
2.500g
$ 1733.00

Matrix Scientific
2-Amino-1-[3-(trifluoromethyl)phenyl]ethanone
1g
$ 1073.00

A1 Biochem Labs
2-Amino-1-[3-(trifluoromethyl)phenyl]ethanone 95%
2.5 g
$ 1050.00

Total 4 raw suppliers

Chemical Property of 2-Amino-1-[3-(trifluoromethyl)phenyl]ethanone

Chemical Property:

PSA：43.09000
LogP:2.54710
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:203.05579836
Heavy Atom Count:14
Complexity:215

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-1-[3-(trifluoromethyl)phenyl]ethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)C(F)(F)F)C(=O)CN

Technology Process of 2-Amino-1-[3-(trifluoromethyl)phenyl]ethanone

There total 2 articles about 2-Amino-1-[3-(trifluoromethyl)phenyl]ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 61062-57-5
2-azido-1-(3-(trifluoromethyl)phenyl)ethanone

: 64748-87-4
2-amino-1-[3-(trifluoromethyl)phenyl]ethanone

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal;
DOI:10.1021/jo00425a023

Reference yield:

: 349-76-8
3'-(trifluoromethyl)acetophenone

: 64748-87-4
2-amino-1-[3-(trifluoromethyl)phenyl]ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: (i) AlCl₃, (ii) Br₂, (iii) NaN₃

2: aq. HCl, H₂ / Pd-C

With hydrogenchloride; hydrogen; palladium on activated charcoal;
DOI:10.1021/jo00425a023

Reference yield: 44.5%

: 57084-54-5
3-bromo-2,2-diethoxypropionic acid

: 64748-87-4
2-amino-1-[3-(trifluoromethyl)phenyl]ethanone

: 1171113-41-9
3-bromo-2,2-diethoxy-N-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}propanamide

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; In tetrahydrofuran; at 20 ℃; Inert atmosphere;
DOI:10.1055/s-0028-1088162