4H-Pyran-4-one, 5-hydroxy-2-[(triphenylmethoxy)methyl]-

Base Information

• Chemical Name: 4H-Pyran-4-one, 5-hydroxy-2-[(triphenylmethoxy)methyl]-
• CAS No.: 64756-79-2
• Molecular Formula: C₂₅H₂₀O₄
• Molecular Weight: 384.431
• Mol file: 64756-79-2.mol

Synonyms:5-Hydroxy-4-oxo-2-trityloxymethyl-4H-pyran;5-hydroxy-2-trityloxymethyl-pyran-4-one;

Chemical Property of 4H-Pyran-4-one, 5-hydroxy-2-[(triphenylmethoxy)methyl]-

Chemical Property:

• Boiling Point: 552.7±50.0 °C(Predicted)
• PSA: 59.67000
• Density: 1.259±0.06 g/cm3(Predicted)
• LogP: 4.85410

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4H-Pyran-4-one, 5-hydroxy-2-[(triphenylmethoxy)methyl]-

There total 4 articles about 4H-Pyran-4-one, 5-hydroxy-2-[(triphenylmethoxy)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one (501-30-4,123712-78-7) + trityl chloride (76-83-5) → 5-hydroxy-2-trityloxymethyl-pyran-4-one (64756-79-2) + 2-hydroxymethyl-5-trityloxy-pyran-4-one

Guidance literature:

With dmap; triethylamine; In dichloromethane; for 2h; Title compound not separated from byproducts; 0 deg C up to RT;

DOI:10.1016/S0040-4039(99)01391-X

Reference yield:

5-benzoyloxy-2-trityloximethyl-pyran-4-one → 5-hydroxy-2-trityloxymethyl-pyran-4-one (64756-79-2)

Guidance literature:

With pyridine; hydroxylamine hydrochloride;

DOI:10.1139/v55-164

Reference yield:

5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one (501-30-4,123712-78-7) + trityl chloride (76-83-5) → 5-hydroxy-2-trityloxymethyl-pyran-4-one (64756-79-2)

Guidance literature:

With pyridine;

upstream raw materials:

5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one

trityl chloride