Benzeneethanesulfonothioic acid, S-(2-phenylethyl) ester

Base Information

• Chemical Name: Benzeneethanesulfonothioic acid, S-(2-phenylethyl) ester
• CAS No.: 64768-46-3
• Molecular Formula: C16H18O2S2
• Molecular Weight: 306.45
• Mol file: 64768-46-3.mol

Synonyms:

Chemical Property of Benzeneethanesulfonothioic acid, S-(2-phenylethyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzeneethanesulfonothioic acid, S-(2-phenylethyl) ester

There total 9 articles about Benzeneethanesulfonothioic acid, S-(2-phenylethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-phenylethylsulfonyl chloride (4025-71-2) → S-phenethyl 2-phenylethane-1-sulfonothioate (64768-46-3)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; In acetone; acetonitrile; at 20 ℃; for 20h; chemoselective reaction;

DOI:10.1002/adsc.201600633

Reference yield: 45.0%

n-butyl-2-phenylethane-1-sulfinamide → S-phenethyl 2-phenylethane-1-sulfonothioate (64768-46-3)

Guidance literature:

With trifluoroacetic acid; In neat (no solvent); at 25 ℃; for 1h;

DOI:10.1039/d1ob01714d

Reference yield: 19.0%

2-phenylethanesulfonyl cyanide → S-phenethyl 2-phenylethane-1-sulfonothioate (64768-46-3)

Guidance literature:

With dipotassium hydrogenphosphate; eosin; 5-Hexen-2-one; In N,N-dimethyl-formamide; at 25 ℃; for 24h; Irradiation; Inert atmosphere;

DOI:10.1021/acs.orglett.8b01828

upstream raw materials:

2-mercaptophenylethane

2-phenylethylsulfonyl chloride

1-phenyl-2-bromoethane

2-phenylethyl thiocyanate

Refernces

• 1、 Pirenne, Vincent,Kurtay, Gülbin,Voci, Silvia,Bouffier, Laurent,Sojic, Neso,Robert, Frédéric,Bassani, Dario M.,Landais, Yannick. "Eosin-Mediated Alkylsulfonyl Cyanation of Olefins". . p. 4521 - 4525. Retrieved 2018/08/09.