eudistomin U

Base Information

• Chemical Name: eudistomin U
• CAS No.: 155885-64-6
• Molecular Formula: C₁₉H₁₃N₃
• Molecular Weight: 283.332
• Mol file: 155885-64-6.mol

Synonyms:EudistominU; Eudistomine U

Chemical Property of eudistomin U

Chemical Property:

• PSA: 41.04000
• LogP: 1.98390

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of eudistomin U

There total 34 articles about eudistomin U which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

C19H19N3 → eudistomin U (155885-64-6)

Guidance literature:

With oxygen; In water; at 20 ℃; for 12h; Irradiation;

DOI:10.1039/d1gc01729b

Reference yield: 89.0%

1-(1H-indol-3-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole (172615-59-7) → eudistomin U (155885-64-6)

Guidance literature:

With oxygen; In 1-methyl-pyrrolidin-2-one; at 150 ℃; for 24h;

DOI:10.1002/jhet.3931

Reference yield: 88.0%

1-(1H-indol-3-yl)-9H-pyrido[3,4-b]indole-3-carboxylic acid → eudistomin U (155885-64-6)

Guidance literature:

With quinoline; copper; at 240 ℃; for 0.166667h; Neat (no solvent); Microwave irradiation; Inert atmosphere;

DOI:10.1039/c1cc11298h

upstream raw materials:

N-ethynyl-4-methyl-N-(2-((trimethylsilyl)ethynyl)phenyl)benzenesulfonamide

C₃₂H₂₄N₂O₄S₂

2-iodophenylamine

2-[(trimethylsilyl)ethynyl]aniline

Refernces

• 1、 Ranjani, Ganapathy,Nagarajan, Rajagopal. "Access to 1-indolyltetrahydro-β-carbolines: via metal-free cross-dehydrogenative coupling: The total synthesis of eudistomin U, isoeudistomin U and 19-bromoisoeudistomin U". . p. 757 - 760. Retrieved 2021.
• 2、 Molina, Pedro,Fresneda, Pilar M.,Garcia-Zafra, Sagrario. "An iminophosphorane-mediated efficient synthesis of the alkaloid eudistomin U of marine origin". . p. 3581 - 3582. Retrieved 1995.
• 3、 Abinaya, R.,Balasubramaniam, K. K.,Baskar, B.,Divya, P.,Mani Rahulan, K.,Rahman, Abdul,Sridhar, R.,Srinath, S.. "Visible light mediated selective oxidation of alcohols and oxidative dehydrogenation of N-heterocycles using scalable and reusable La-doped NiWO4nanoparticles". . p. 5990 - 6007. Retrieved 2021/08/24.
• 4、 Abinaya, R.,Baskar, B.,Mariappan, M.,Prasanth, Arun,Sridhar, R.,Srinath, S.. "Reusable, homogeneous water soluble photoredox catalyzed oxidative dehydrogenation of N-heterocycles in a biphasic system: Application to the synthesis of biologically active natural products". . p. 2575 - 2587. Retrieved 2020/05/13.