N-(8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-2,3-dimethoxy-benzamide

Base Information

Chemical Name:N-(8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-2,3-dimethoxy-benzamide
CAS No.:76352-13-1
Molecular Formula:C23H28 N2 O3
Molecular Weight:380.487
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90875446
ChEMBL ID:CHEMBL75876
Mol file:76352-13-1.mol

Synonyms:CHEMBL75876;SCHEMBL2110411;DTXSID90875446;BDBM50010728;N-(8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-2,3-dimethoxy-benzamide

Suppliers and Price of N-(8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-2,3-dimethoxy-benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TROPAPRIDE 95.00%
5MG
$ 500.85

Total 6 raw suppliers

Chemical Property of N-(8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-2,3-dimethoxy-benzamide

Chemical Property:

Vapor Pressure:1.45E-10mmHg at 25°C
Boiling Point:511.2°C at 760 mmHg
Flash Point:263°C
PSA：50.80000
Density:1.2g/cm³
LogP:3.95800
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:380.20999276
Heavy Atom Count:28
Complexity:508

Purity/Quality:

99% ^*data from raw suppliers

TROPAPRIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=C1OC)C(=O)NC2CC3CCC(C2)N3CC4=CC=CC=C4

Technology Process of N-(8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-2,3-dimethoxy-benzamide

There total 1 articles about N-(8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-2,3-dimethoxy-benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1521-38-6
2,3-dimethoxybenzoic acid

: 76272-36-1
8-benzyl-8-aza-bicyclo[3.2.1]oct-3-yl-amine

: 76352-13-1
Tropapride

Guidance literature:: 2,3-dimethoxybenzoic acid; With chloroformic acid ethyl ester; triethylamine; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

8-benzyl-8-aza-bicyclo[3.2.1]oct-3-yl-amine; In N,N-dimethyl-formamide; for 24h;
DOI:10.1016/j.ejmech.2011.07.022

Reference yield: 91.6%

: 76352-13-1
Tropapride

: exo-2,3-Dimethoxy-N-<8-azabicyclo<3.2.1>oct-3-yl>benzamide hydrochloride

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; for 24h; under 7600.51 Torr;
DOI:10.1016/j.ejmech.2011.07.022

Reference yield:

: 76352-13-1
Tropapride

: N-(8-(pyridin-2-ylmethyl)-8-azabicyclo[3.2.1]oct-3β-yl)-2,3-dimethoxybenzamide dihydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: palladium on activated charcoal; hydrogen / methanol / 24 h / 7600.51 Torr

2: potassium carbonate; potassium iodide / acetone / 1 h / Reflux

With palladium on activated charcoal; hydrogen; potassium carbonate; potassium iodide; In methanol; acetone;
DOI:10.1016/j.ejmech.2011.07.022