Bromobenzene-3,4-dihydrodiol

Base Information

Chemical Name:Bromobenzene-3,4-dihydrodiol
CAS No.:82683-93-0
Molecular Formula:C₆H₇BrO₂
Molecular Weight:191.024
Hs Code.:
DSSTox Substance ID:DTXSID801002845
Nikkaji Number:J2.790.487D
Wikidata:Q27116165

Synonyms:Bromobenzene-3,4-dihydrodiol;82683-93-0;3,5-Cyclohexadiene-1,2-diol, 4-bromo-;4-bromocyclohexa-3,5-diene-1,2-diol;SCHEMBL8110340;CHEBI:34588;DTXSID801002845;4-Bromo-3,5-cyclohexadiene-1,2-diol;3,4-dihydro-3,4-dihydroxy-bromobenzene;Q27116165

Suppliers and Price of Bromobenzene-3,4-dihydrodiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Bromobenzene-3,4-dihydrodiol

Chemical Property:

Vapor Pressure:0.000117mmHg at 25°C
Boiling Point:299.7°Cat760mmHg
Flash Point:135.1°C
Density:1.922g/cm³
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:189.96294
Heavy Atom Count:9
Complexity:162

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(C1O)O)Br

Technology Process of Bromobenzene-3,4-dihydrodiol

There total 7 articles about Bromobenzene-3,4-dihydrodiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 121073-20-9
(5α,6β)-2-bromo-5-hydroxy-6-<<(1,1-dimethylethyl)dimethylsilyl>oxy>cyclohexa-1,3-diene

: 67451-63-2,82683-93-0,121073-22-1
trans-1,2-dihydroxy-1,2-dihydro-4-bromobenzene

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 1h; Ambient temperature;
DOI:10.1021/jo00273a005

Reference yield:

: 121073-14-1
1-bromo-3-<<(1,1-dimethylethyl)dimethylsilyl>oxy>cyclohexa-1,4-diene

: 67451-63-2,82683-93-0,121073-22-1
trans-1,2-dihydroxy-1,2-dihydro-4-bromobenzene

Guidance literature:: Multi-step reaction with 4 steps

1: 44 percent / sodium phosphate, m-CPBA / CHCl₃ / 43 h / Ambient temperature

2: 30 percent / NaBH₄ / methanol / 1.) 0 deg C, 12 h, 2.) RT, 24 h

3: 67 percent / sodium phosphate, tetrabutylammonium periodate / CHCl₃ / 14 h / Ambient temperature

4: 75 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1 h / Ambient temperature

With sodium tetrahydroborate; tetrabutyl ammonium fluoride; tetrabutylammonium periodite; 3-chloro-benzenecarboperoxoic acid; sodium phosphate; In tetrahydrofuran; methanol; chloroform;
DOI:10.1021/jo00273a005

Reference yield:

: 121073-08-3
3-bromo-6-(phenylseleno)cyclohex-2-en-1-one

: 67451-63-2,82683-93-0,121073-22-1
trans-1,2-dihydroxy-1,2-dihydro-4-bromobenzene

Guidance literature:: Multi-step reaction with 7 steps

1: 79 percent / NaBH₄, CeCl₃*7H₂O / ethanol / 1.5 h / 0 - 20 °C

2: Et₃N, DMAP / CH₂Cl₂ / 50 h / Heating

3: sodium phosphate, tetrabutylammonium periodate / CHCl₃ / 24 h

4: 44 percent / sodium phosphate, m-CPBA / CHCl₃ / 43 h / Ambient temperature

5: 30 percent / NaBH₄ / methanol / 1.) 0 deg C, 12 h, 2.) RT, 24 h

6: 67 percent / sodium phosphate, tetrabutylammonium periodate / CHCl₃ / 14 h / Ambient temperature

7: 75 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1 h / Ambient temperature

With dmap; sodium tetrahydroborate; cerium(III) chloride; tetrabutyl ammonium fluoride; tetrabutylammonium periodite; triethylamine; 3-chloro-benzenecarboperoxoic acid; sodium phosphate; In tetrahydrofuran; methanol; ethanol; dichloromethane; chloroform;
DOI:10.1021/jo00273a005