7H-1,3,4-Thiadiazolo[3,2-a]pyridine-7,8-dicarboxylic acid, 5-(diethylamino)-2-(4-methoxyphenyl)-6-methyl-7-(4-nitrophenyl)-, diethyl ester

Base Information

• Chemical Name: 7H-1,3,4-Thiadiazolo[3,2-a]pyridine-7,8-dicarboxylic acid, 5-(diethylamino)-2-(4-methoxyphenyl)-6-methyl-7-(4-nitrophenyl)-, diethyl ester
• CAS No.: 64874-30-2
• Molecular Formula: C₃₀H₃₄N₄O₇S
• Molecular Weight: 594.689
• Mol file: 64874-30-2.mol

Synonyms:

Chemical Property of 7H-1,3,4-Thiadiazolo[3,2-a]pyridine-7,8-dicarboxylic acid, 5-(diethylamino)-2-(4-methoxyphenyl)-6-methyl-7-(4-nitrophenyl)-, diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7H-1,3,4-Thiadiazolo[3,2-a]pyridine-7,8-dicarboxylic acid, 5-(diethylamino)-2-(4-methoxyphenyl)-6-methyl-7-(4-nitrophenyl)-, diethyl ester

There total 5 articles about 7H-1,3,4-Thiadiazolo[3,2-a]pyridine-7,8-dicarboxylic acid, 5-(diethylamino)-2-(4-methoxyphenyl)-6-methyl-7-(4-nitrophenyl)-, diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(4-methoxy-phenyl)-3-(4-nitro-phenyl)-[1,3,4]thiadiazolium; chloride (35222-94-7) → 5-diethylamino-2-(4-methoxy-phenyl)-6-methyl-7-(4-nitro-phenyl)-7H-[1,3,4]thiadiazolo[3,2-a]pyridine-7,8-dicarboxylic acid diethyl ester (64874-30-2)

Guidance literature:

Multi-step reaction with 3 steps

1: iPr₂NEt

2: benzene

With N-ethyl-N,N-diisopropylamine; In benzene;

DOI:10.1016/S0040-4039(01)83689-3

Reference yield:

2-methoxy-5-(4-methoxy-phenyl)-3-(4-nitro-phenyl)-2,3-dihydro-[1,3,4]thiadiazole (66380-23-2) → 5-diethylamino-2-(4-methoxy-phenyl)-6-methyl-7-(4-nitro-phenyl)-7H-[1,3,4]thiadiazolo[3,2-a]pyridine-7,8-dicarboxylic acid diethyl ester (64874-30-2)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene

In benzene;

DOI:10.1016/S0040-4039(01)83689-3

Reference yield:

acetylenedicarboxylic acid diethyl ester (762-21-0) → 5-diethylamino-2-(4-methoxy-phenyl)-6-methyl-7-(4-nitro-phenyl)-7H-[1,3,4]thiadiazolo[3,2-a]pyridine-7,8-dicarboxylic acid diethyl ester (64874-30-2)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene

In benzene;

DOI:10.1016/S0040-4039(01)83689-3

upstream raw materials:

methyl(diethylamino)acetylene

5-(4-methoxy-phenyl)-3-(4-nitro-phenyl)-[1,3,4]thiadiazolium; chloride

2-methoxy-5-(4-methoxy-phenyl)-3-(4-nitro-phenyl)-2,3-dihydro-[1,3,4]thiadiazole

acetylenedicarboxylic acid diethyl ester