Chemical Property of bursicon
Chemical Property:
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Description
Bursicon is a heterodimer glycoprotein hormone that is
involved in the regulation of ecdysis and postecdysis processes
associated with expansion, tanning, and sclerotization of the
cuticle as well as feeding behavior in insects and innate
immunity in crustaceans.
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Biological functions
In D. melanogaster, bursicon controls cuticle sclerotization
and melanization.In D. melanogaster, B. mori, and
the beetle Tribolium castaneum, it is necessary for the
expansion and hardening of the wings.The expansion
of wings requires bursicon-induced extensibility of the
wing cuticle, as demonstrated in the moth M. sexta.In
D. melanogaster, burs-β is an important signal for controlling
ecdysis behavior.In the crab C. sapidus, bursicon
controls the deposition and thickening of the new cuticle
as well as the granulation of hemocytes.In both Procambarus
clarkii and D. melanogaster, bursicon homodimers
induce innate immunity by altering antimicrobial peptides
via Relish.Besides, burs-α in D. melanogaster
binds to its neuronal receptor DLgr2, eventually regulating
organismal resistance to metabolic challenges
through Adipokinetic hormone signaling.
