azepinomycin 3-ribofuranoside

Base Information

• Chemical Name: azepinomycin 3-ribofuranoside
• CAS No.: 115173-45-0
• Molecular Formula: C₁₁H₁₆N₄O₆
• Molecular Weight: 300.271
• Mol file: 115173-45-0.mol

Synonyms:azepinomycin 3-ribofuranoside

Chemical Property of azepinomycin 3-ribofuranoside

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 920.8°C at 760 mmHg
• Flash Point: 510.7°C
• PSA: 152.59000
• Density: 2.11g/cm³
• LogP: -2.88330

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of azepinomycin 3-ribofuranoside

There total 5 articles about azepinomycin 3-ribofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

5-(2,2-diethoxyethylamino)-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide (119138-94-2) → 3-β-D-ribofuranosylazepinomycin (115173-45-0)

Guidance literature:

With hydrogenchloride; for 1h; Ambient temperature;

DOI:10.1248/cpb.42.1231

Reference yield:

N'-benzyloxy-5-(2,2-diethoxyethylamino)-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamidine (119139-12-7) → 3-β-D-ribofuranosylazepinomycin (115173-45-0)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂, HCl / Raney Ni W-2 / H₂O / 6 h / Ambient temperature

2: 1N aq. NaOH / 0.5 h / Heating

3: 94 percent / 1N aq. HCl / 1 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; hydrogen; Raney Ni W-2; In water;

DOI:10.1248/cpb.42.1231

Reference yield:

N'-benzyloxy-5--1-β-D-ribofuranosyl-1H-imidazole-4-carboxamidine (119139-11-6) → 3-β-D-ribofuranosylazepinomycin (115173-45-0)

Guidance literature:

Multi-step reaction with 4 steps

1: 339 mg / 1N aq. NaOH / 2 h / Ambient temperature

2: H₂, HCl / Raney Ni W-2 / H₂O / 6 h / Ambient temperature

3: 1N aq. NaOH / 0.5 h / Heating

4: 94 percent / 1N aq. HCl / 1 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; hydrogen; Raney Ni W-2; In water;

DOI:10.1248/cpb.42.1231

upstream raw materials:

5-(2,2-diethoxyethylamino)-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide

N'-benzyloxy-5-(2,2-diethoxyethylamino)-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamidine

N'-benzyloxy-5--1-β-D-ribofuranosyl-1H-imidazole-4-carboxamidine

N'-benzyloxy-5-formamido-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamidine

Refernces