1-Ethyl-4-(3-methoxyphenyl)-1,2,3,6-tetrahydropyridine

Base Information

Chemical Name:1-Ethyl-4-(3-methoxyphenyl)-1,2,3,6-tetrahydropyridine
CAS No.:102538-16-9
Molecular Formula:C14H19 N O
Molecular Weight:0
Hs Code.:
DSSTox Substance ID:DTXSID40145262
Wikidata:Q83009715
ChEMBL ID:CHEMBL35779
Mol file:102538-16-9.mol

Synonyms:1-ethyl-4-(3-methoxyphenyl)-1,2,3,6-tetrahydropyridine;N-ET-MO-MPTP

Suppliers and Price of 1-Ethyl-4-(3-methoxyphenyl)-1,2,3,6-tetrahydropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1-Ethyl-4-(3-methoxyphenyl)-1,2,3,6-tetrahydropyridine

Chemical Property:

Vapor Pressure:0.000152mmHg at 25°C
Boiling Point:331.8°Cat760mmHg
Flash Point:98°C
PSA：12.47000
Density:1.012g/cm³
LogP:2.74210
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:217.146664230
Heavy Atom Count:16
Complexity:249

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1CCC(=CC1)C2=CC(=CC=C2)OC

Technology Process of 1-Ethyl-4-(3-methoxyphenyl)-1,2,3,6-tetrahydropyridine

There total 4 articles about 1-Ethyl-4-(3-methoxyphenyl)-1,2,3,6-tetrahydropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 102573-71-7
1-ethyl-4-hydroxy-4-(3-methoxyphenyl)piperidine

: 102538-16-9
1,2,3,6-tetrahydro-4-(3-methoxyphenyl)-N-ethylpyridine

Guidance literature:: With phosphoric acid; at 70 - 80 ℃; for 3h;
DOI:10.1021/jm00158a033

Reference yield:

: 104-15-4
toluene-4-sulfonic acid

: 102538-16-9
1,2,3,6-tetrahydro-4-(3-methoxyphenyl)-N-ethylpyridine

Guidance literature:: With sodium hydroxide; In water; toluene;

Reference yield:

: 3612-18-8
N-ethyl-4-piperidone

: 102538-16-9
1,2,3,6-tetrahydro-4-(3-methoxyphenyl)-N-ethylpyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-butyllithium / 1.) THF, -78 deg C, 30 min, 2.) THF, -20 deg C, 2 h

2: 90 percent / 85percent aq. phosphoric acid / 3 h / 70 - 80 °C

With n-butyllithium; phosphoric acid;
DOI:10.1021/jm00158a033